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Journal of Cardio-Thoracic Medicine، جلد ۱۱، شماره ۲، صفحات ۱۱۶۷-۱۱۷۶
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عنوان انگلیسی Association of Venous Thromboembolism and Inflammatory Bowel Disease
چکیده انگلیسی مقاله Introduction: Studies have shown that patients with inflammatory bowel disease (IBD) have an increased risk for venous thromboembolism (VTE). VTEs causes significant morbidity and mortality.Methods: We carried out a comprehensive search through different online databases including PubMed, Google Scholar, Scopus, and Medline. We focused on some of patients-related factors that may affect the risk of VTE incidence among IBD patients and also reviewed current guidelines on the prophylactic regimen of the IBD patients.Results: Based on the previous studies, the hypercoagulable nature of the disease results from a complex interaction between the systems participating in the coagulation cascade, including endothelial cells, platelets, and coagulation factors. There are a number of clinical factors that increase the probability of VTE development which include disease activity, age, pregnancy, surgery, and medical treatment.Conclusion: Taken together, these data suggest to initiate prophylactic regimen in IBD patients and to adjust it regarding to the patient’s condition and the presence of other predisposing factors.
کلیدواژه‌های انگلیسی مقاله Inflammatory bowel disease, Venous thromboembolism, Inflammation, Prevention
نویسندگان مقاله | Mitra Ahadi
Department of Gastroenterology and Hepatology, Mashhad University of Medical Sciences, Mashhad, Iran.


| Nikoo Saeedi
Student Research Committee, Islamic Azad University, Mashhad Branch, Mashhad, Iran.


| Mina Akbari Rad
Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Negin Masoudifar
Department of Internal Medicine, University of Toronto, Toronto, Canada.
نشانی اینترنتی https://jctm.mums.ac.ir/article_22671.html
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نوع مقاله منتشر شده Review Article
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