این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Acta Medica Iranica، جلد ۶۱، شماره ۴، صفحات ۲۰۴-۲۱۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Seminal Histone Deacetylase, Fructose and Serum Reproductive Hormones as Diagnostic Marker in Sub-Groups of Infertile Males
چکیده انگلیسی مقاله Accurate diagnosis of the cause of infertility assists in the choice of treatment modalities and amelioration of the associated psychosocial problems. The research was carried out using 75 infertile males and 75 males with proven fertility as controls. The anthropometrics (weight, height) were measured and body mass index (BMI) computed. Venous blood was collected from each participant, allowed to clot, and centrifuged to obtain the serum which was analysed for testosterone, follicle stimulating hormone (FSH) and luteinizing hormone (LH) concentrations. Semen was collected by masturbation and analysed for sperm quality, seminal fructose concentration, and histone deacetylase (HDAC) activities. A non-significant difference (P>0.05) in weight, height, and BMI; a significant increase (P< 0.05) in ejaculated volume, serum LH, FSH, seminal fructose concentrations and HDAC activities; and a decrease in sperm count, sperm motility, serum testosterone concentration was observed among subgroups of infertile men. A direct and significant correlation exists between seminal HDAC activities and fructose concentration. Also, an inverse non-significant correlation exists between HDAC activities and spermatozoa motility. Base on the result obtained from this study, it can be concluded that measuring seminal fructose and HDAC activities in addition to routine biochemical and biophysical parameters will assist in diagnostic work up in subgroups of male infertility.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Wasiu Olooto
Department of Chemical Pathology and Immunology, Olabisi Onabanjo University, Ago-Iwoye, Ogun, Nigeria


| Hammed Adenusi
Department of Chemical Pathology and Immunology, Olabisi Onabanjo University, Ago-Iwoye, Ogun, Nigeria


| Joseph Soola
Department of Physiology, Olabisi Onabanjo University, Ago-Iwoye, Ogun, Nigeria


| Monisola Ayodele
Department of Chemical Pathology and Immunology, Olabisi Onabanjo University, Ago-Iwoye, Ogun, Nigeria


| Frank Agidigbi
School of Medical Laboratory Technology, Baptist Medical Center, Saki, Nigeria
نشانی اینترنتی https://acta.tums.ac.ir/index.php/acta/article/view/9261
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات