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Iranian Journal of Nursing and Midwifery Research، جلد ۲۱، شماره ۵، صفحات ۴۵۸-۰
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عنوان انگلیسی Antimicrobial effects of chlorhexidine, matrica drop mouthwash (chamomile extract), and normal saline on hospitalized patients with endotracheal tubes
چکیده انگلیسی مقاله ABSTRACT Background: The functions and use of mouthwashes are variable depending on their type. Oral care in patients with endotracheal tubes is important to prevent side effects such as pneumonia. The aim of this study was to determine the antimicrobial effects of chlorhexidine, drop of Matrica mouthwash (chamomile extract), and normal saline on hospitalized patients with endotracheal tube in an intensive care unit (ICU). Materials and Methods: In this clinical trial, 39 patients admitted to the ICU were selected by convenience sampling, were matched based on age and sex, and randomly assigned to three groups (chlorhexidine, Matrica, saline). Mouth washing was performed every 8 to 48 hours. The samples were taken at time zero (before the intervention) and 48 hours after the intervention for bacterial culture. Antibacterial activity of each mouthwash on microorganisms was measured based on the growth of Staphylococcus aureus , Pneumococcal , Enterococcus , Pseudomonas , and Escherichia coli . The obtained data were then analyzed using Chi-square and Fisher’s exact tests with the Statistical Package for the Social Sciences Package version 18. Results: Chlorhexidine mouthwash was more effective in preventing colonization of bacteria in the mouth (point probability = 0.06) in comparison with chamomile and saline mouthwashes. Nevertheless, none of the tested mouthwashes were able to remove pathogens, including Staphylococcus aureus , Pseudomonas , Klebsiella , and Acinetobacter . Conclusions: 0.2% chlorhexidine mouthwash has a significant effect on the bacterial colonization rate in comparison with Matrica and normal saline mouthwashes in ICU hospitalized patients with endotracheal tube.
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نویسندگان مقاله مریم عظیمی | maryam azimi


لیلا جویباری | leyla jouybari


شهرام مقدم | shahram moghadam


عزت اله قایمی | ezatollah ghaemi


ناصر بهنام پور | naser behnam pour


اکرم ثناگو | akram sanagou


مسلم حسام | moslem hesam


نشانی اینترنتی http://www.ijnmr.mui.ac.ir/index.php/ijnmr/article/view/1344
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