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Molecular Biology Research Communications، جلد ۱۲، شماره ۳، صفحات ۱۰۹-۱۱۵
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عنوان انگلیسی The effect of RORA (RAR-Related Orphan Receptor Alpha) receptors on litter size in Akkaraman sheep breed
چکیده انگلیسی مقاله In this study, the relationship between RORA 23bp indel genotype and allele frequency with twin pregnancy, fertility, live weight and milk yield in 106 female Akkaraman ewes raised in Elazığ province was investigated. In the study conducted in Elâzığ province, 10ml milk was collected from 106 Akkaraman sheep and DNA was extracted from these milk. In RORA 23bp indel genotype frequency, DD genotype was found more than ID and II genotypes and RORA 23bp indel ın allele frequency, the D allele was found to be higher than the I allele. In both the first and second parity, the twinning rate was found to be lower. In both the first and second parity, the twinning rate was higher in the DD genotype, and it was observed that this genotype promınated mıddle lıvestock weıght and mılk yıeld. According to the results of our study, mutations in the RORA gene, which is a gene affecting reproductive efficiency in sheep, do not have a positive effect on fertility and twinning rate in Akkaraman sheep. To sum, this study provided theoretical references for the comprehensively research of the function of RORA gene and the breeding of Akkaraman Sheep. The 23-bp indel variants can be considered as molecular markers for litter size of sheep for marker-assisted selection breeding.
کلیدواژه‌های انگلیسی مقاله Sheep, RORA, Insertion/deletion (Indel), Mmutation, Litter size
نویسندگان مقاله Serbulent Yiğit |
Department of Genetics, Faculty of Veterinary Medicine, Ondokuz Mayis University, Samsun, Turkiye

Selim Kul |
Faculty of Veterinary Medicine, Department of Animal Breeding, Fırat University, Elazig, Turkiye

Recai Aci |
Department of Biochemistry, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun, Turkiye

Adem Keskin |
University Faculty of Medicine, Department of Biochemistry, Aydın, Turkiye

Tuğçe Tuygun |
Department of Parasitology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun, Turkiye

Esra Duman |
Department of Gastrology and Hepatology, Faculty of Medicine, Kocaeli University, Kocaeli, Turkiye

نشانی اینترنتی https://mbrc.shirazu.ac.ir/article_7073_0fd47f202d5170a65c1dfef416149519.pdf
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