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Iranian Journal of Blood and Cancer، جلد ۱۵، شماره ۲، صفحات ۸۹-۹۶
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عنوان انگلیسی Guideline for the diagnosis and treatment of hypothyroidism and hypoparathyroidism in patients with blood transfusion-dependent thalassemia
چکیده انگلیسی مقاله Iron overload can adversely affect thyroid and parathyroid function in patients with transfusion-dependent thalassemia. Iron deposition in both glands or the pituitary gland, which controls thyroid function, can lead to their destruction and dysfunction. Hypothyroidism can cause symptoms such as fatigue, weight gain, and depression, while hypoparathyroidism can cause symptoms such as numbness and tingling in the hands and feet, muscle cramps, and seizures. Regular thyroid and parathyroid function monitoring is essential in thalassemia patients to detect any dysfunction early and provide appropriate treatment. Treatment may include medications to replace thyroid hormone or calcium and vitamin D supplements to manage hypoparathyroidism. A comprehensive approach to managing endocrine complications in thalassemia patients can improve outcomes and quality of life for these individuals. To provide professional healthcare members with clear and concise recommendations for diagnosing and treating hypothyroidism and hypoparathyroidism in transfusion dependent thalassemia patients, a practical national guideline should be developed.
کلیدواژه‌های انگلیسی مقاله Transfusion Dependent Thalassemia, Hypothyroidism, Hypoparathyroidism, Iron overload, Iron chelators
نویسندگان مقاله | Nahid Hashemi-madani
Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.


| Neda Rahimian
Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.


| Mohammad E. Khamseh
Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.


| Pooya Faranoush
Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran


| Mojtaba Malek
Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.


| Fariba Ghasemi
Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran


| Negin Sadighnia
Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran


| Mohammad Reza Foroughi-Gilvaee
Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran


| Seyyed Morteza Alavi
Department of Clinical Science, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran


| Mohammad Javad Mashayekhnia
Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, Islamic Azad University, Babol Branch, Tabriz, Iran


| Mahdi Bashizade
Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.


| Mohammad Reza Roudaki Sarvendani
Department of Veterinary Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.


| Elham Ebrahimi
Department of Clinical Science, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran


| Mohammad Faranoush
Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran.
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-41-2&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pediatric Hematology & Oncology
نوع مقاله منتشر شده پژوهشی
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