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JCR 2016
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چهارشنبه 26 آذر 1404
Iranian Journal of Microbiology
، جلد ۱۵، شماره ۴، صفحات ۵۱۳-۵۲۰
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عنوان انگلیسی
Prevalence of Gardnerella vaginalis infection and antibiotic resistance pattern of isolates of gynecology clinic patients at Shahriar Noor Hospital from January to June 2020 by PCR and culture methods
چکیده انگلیسی مقاله
Background and Objectives: Gardnerella vaginalis is one of the most important causes of prevalent genital infections that pose serious risks. This study aimed to determine the prevalence of Gardnerella vaginalis and antibiotic resistance pattern of isolates of patients referred to the gynecology clinic of Shahriar Noor Hospital by PCR and culture methods. Materials and Methods: The study was conducted on 500 patients who had suffered from a vaginal infection. The demographic data of patients were studied. For diagnosis of Gardnerella vaginalis isolates, cultivation in anaerobic conditions, biochemical tests, PCR and Gardnerella vaginalis antibiotic susceptibility test to metronidazole and clindamycin were performed. Data analysis was performed utilizing SPSS statistical software version 19 and the Chi-square test. Results: Among the 500 patients, 173 were diagnosed with Gardnerella vaginitis. There was a significant relationship between age group, level of education, and contraceptive method with Gardnerella vaginosis incidence. Performing antibiotic susceptibility tests showed that the resistance of Gardnerella vaginalis isolated strains to metronidazole and clindamycin was 86.12% and 17.34%, respectively. Conclusion: The high prevalence of Gardnerella vaginalis infections confirms the critical role of the bacterium in the occurrence of bacterial vaginosis. Therefore, it is necessary to check the prevalence of bacterial infections to recommend the correct medical treatment in different societies.
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نویسندگان مقاله
| Saghi Rashidifar
Department of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran
| Naser Harzandi
Department of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran
| Sahar Honarmand Jahromi
Department of Microbiology, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran
| Mohammad Javad Gharavi
Department of Parasitology, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی
https://ijm.tums.ac.ir/index.php/ijm/article/view/3604
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