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Iranian Journal of Blood and Cancer، جلد ۱۵، شماره ۴، صفحات ۲۱۲-۲۳۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Review of endocrine complications in transfusion-dependent thalassemia
چکیده انگلیسی مقاله Beta thalassemia is an inherited genetic disorder that often leads to transfusion dependence. One of the significant issues that these patients face is increased iron accumulation in their bodies due to the nature of the disease and regular blood transfusions. Iron overload can cause hemosiderosis and tissue damage in various organs, including the heart, liver, and endocrine systems. Endocrine problems are one of the most common complications in transfusion-dependent thalassemia, and addressing these complications can significantly improve patients' health-related quality of life. The prevalence of endocrinopathy is high, especially in patients with poor compliance with therapy. The most common endocrine disorders include hypogonadism, growth disturbances, short stature, delayed puberty, acquired hypothyroidism and hypoparathyroidism, adrenal dysfunction, osteoporosis, diabetes, fertility issues, and complications during pregnancy. Timely diagnosis and treatment of endocrine disorders can improve patients' quality of life and reduce social problems. This article reviews the literature on the various endocrine complications encountered in thalassemia.  
کلیدواژه‌های انگلیسی مقاله Iron overload, Endocrinopathy, Thalassemia, Blood transfusion
نویسندگان مقاله | Pooya Faranoush
Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran


| Ali Elahinia
Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran


| Amir Ziaee
Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran


| Mohammad Faranoush
Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran
نشانی اینترنتی http://ijbc.ir/browse.php?a_code=A-10-41-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pediatric Hematology & Oncology
نوع مقاله منتشر شده مقاله مروری
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