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Journal of Research in Medical Sciences، جلد ۲۸، شماره ۳۶، صفحات ۲۸-۱
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عنوان انگلیسی Effects of probiotic supplementation on semen parameters after varicocelectomy: A randomized controlled trial
چکیده انگلیسی مقاله Background: The use of probiotics in the treatment of infertility is a new area of research. In this study, our objective was to examine the efficacy of probiotic supplementation on semen parameters following varicocelectomy. Materials and Methods: We included infertile men in our study who were the candidates for subinguinal microscopic varicocelectomy. After the surgical procedure, the patients were randomly assigned into two groups: 38 individuals received probiotic upplementation (FamiLact®), while 40 individuals received a placebo for 3 months. We compared the preoperative semen parameters with the postoperative parameters to evaluate the effects of probiotic supplementation. Results: A total of 78 patients were included in the study. The two groups were similar in terms of age, body mass index, infertility period, and semen parameters at baseline (P > 0.05). A statistically significant difference was found in sperm concentration (33.7 ± 22.5 vs. 21.1 ± 16.1 × 106/mL, P = 0.046), and the percentage of sperms with normal morphology (15.0 ± 8.9 vs. 12.0 ± 11.5, P = 0.016) at 3 months favoring the probiotic group. Although the probiotic group exhibited higher values for semen volume and sperm motility at 3 months, the differences were not statistically significant (P = 0.897 and P = 0.177, respectively). Conclusion: Our study demonstrates that the short?term use of probiotics after varicocelectomy can provide additional benefits in improving semen parameters. Probiotic supplements are cost?effective and well tolerated, making them a suitable option for enhancing the outcomes of varicocelectomy.
کلیدواژه‌های انگلیسی مقاله Fertility agents, infertility, probiotic, semen analysis, sperm, varicocelectomy
نویسندگان مقاله | Mousa Asadi


| Farshad Gholipour


| Amirhossein Rahavian


| Mohammad Javanbakht


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/11488
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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