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Cell Journal، جلد ۲۳، شماره ۷، صفحات ۷۷۲-۷۷۸
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چکیده فارسی مقاله
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عنوان انگلیسی Safety and Efficacy of Allogeneic Adipose Tissue Mesenchymal Stromal Cells in Amyotrophic Lateral Sclerosis Patients, Single-Center, Prospective, Open-Label, Single-Arm Clinical Trial, Long-Term Follow-up
چکیده انگلیسی مقاله Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with very limited treatment options. Stem cells have been raised as a new treatment modality for these patients. We have designed a single-center, prospective, open-label, and single arm clinical trial to assess the safety, feasibility, and rather efficacy of administrating allogeneic adipose-derived mesenchymal stromal cells (Ad-MSCs) in ALS patients. We enrolled 17 patients with confirmed ALS diagnosis with ALS Functional Rating Scale-Revised (ALSFRS-R) (
کلیدواژه‌های انگلیسی مقاله Allogeneic Cells, Amyotrophic Lateral Sclerosis, Autologous Cell Transplantation, Mesenchymal Stromal Cells, Stem cells
نویسندگان مقاله Seyed Massood Nabavi |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran

Shahedeh Karimi Karimi |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran

Leila Arab |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran

Leila Sanjari |
International Medicine Department, Mostafa Khomeini Medical Center, Shahed University, Tehran, Iran

Soura Mardpour |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran

Vajiheh Azimian |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran;Core Research Facilities (CRF), Isfahan University of Medical Sciences, Isfahan, Iran

Neda Jarughi |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran

Azadeh Ghaheri |
4Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

Seyedeh-Esmat Hosseini |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran;5Nursing Care Research Center, School of Nursing and Midwifery, Iran University of Med

Nasser Aghdami |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran

Massoud Vosough |
Department of Regenerative Medicine, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, Tehran, Iran

نشانی اینترنتی https://www.celljournal.org/article_250775_b86ed5ea6c58cced1f2f417579c45102.pdf
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