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International Journal of Fertility and Sterility، جلد ۱۷، شماره ۴، صفحات ۲۴۸-۲۵۳
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عنوان انگلیسی Evaluation of Microbial Profile in Patients with Polycystic Ovary Syndrome and Periodontal Disease: A Case-Control Study
چکیده انگلیسی مقاله Background: Polycystic ovary syndrome (PCOS) and oral health are found to share a reciprocal link. Previous substantiating
evidences suggest that PCOS may have a confounding effect on periodontal health and may quantitatively modify
the composition of the oral microbiome. To analyze the role of PCOS as a risk factor in causing periodontal disease, we
compared and evaluated the levels of Porphyromonas gingivalis and Fusobacterium nucleatum in patients with polycystic
ovary syndrome, polycystic ovary syndrome, chronic periodontitis, polycystic ovary syndrome, and gingivitis, and
healthy controls.
Materials and Methods: In this case-control study, 40 female participants are enrolled and grouped into four groups
which included healthy female individuals, patients with PCOS, patients with PCOS and gingivitis, and patients with
PCOS and periodontitis. Periodontal examination is assessed primarily on all the participants using a UNC-15 probe.
Dental plaque is then collected using a sterile curette in one stroke and transferred into an Eppendorf tube containing
TE Buffer (Tris-EDTA buffer) solution. The level of Porphyromonas gingivalis and Fusobacterium nucleatum was
estimated by real-time polymerase chain reaction (PCR).
Results: The levels of Fusobacterium nucleatum were observed to be significantly higher in group with patients with
PCOS and periodontitis.
Conclusion: PCOS may have an impact on the composition of oral microflora causing repercussions in periodontal
health.
کلیدواژه‌های انگلیسی مقاله Dental plaque, Periodontitis, Polycystic Ovary Syndrome
نویسندگان مقاله Reshma Achu Joseph |
Department of Periodontology, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

Supraja Ajitkumar |
Department of Periodontology, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

Subbusamy Kanakasabapathy Balaji |
Department of Periodontology, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

Muthukumar Santhanakrishnan |
Department of Periodontology, Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India

نشانی اینترنتی https://www.ijfs.ir/article_705267_1d81d7eec3a899c091e8cead3c7b163b.pdf
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