این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Fertility and Sterility، جلد ۱۵، شماره ۱، صفحات ۵۱-۵۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Synbiotic Supplementation Improves Metabolic Factors and Obesity Values in Women with Polycystic Ovary Syndrome Independent of Affecting Apelin Levels: A Randomized Double-Blind Placebo-Controlled Clinical Trial
چکیده انگلیسی مقاله Background: This research investigated the symbiotic supplement influences on serum glycemic indices and lipids
as well as apelin rates and obesity values in polycystic ovary syndrome (PCOS) patients.

Materials and Methods: A total of 68 obese or overweight patients (20-44 years old) with PCOS were enrolled to
conduct a randomized double-blinded placebo-controlled clinical trial. A total of 34 people in the synbiotic group received
a synbiotic supplement and 34 people in the placebo group received placebo, daily for 8 weeks. Fasting blood
specimens, anthropometric measurements and dietary intake data were gathered three times during the study. The
information was analyzed by independent t test, paired t test, analysis of covariance and chi-square test.

Results: Synbiotic supplementation significantly decreased serum fasting glucose (P=0.02), insulin (P=0.001), homeostatic
model assessment for insulin resistance (IR, P=0.001), weight (P=0.02), body mass index (BMI, P=0.02),
waist circumference (WC, P=0.01), hip circumference (HC, P=0.02), and waist-to-height ratio (WHtR, P=0.02) but
significantly increased high-density lipoprotein (HDL) cholesterol (P=0.02) compared to the placebo. At the end of the
trial, no significant differences were seen in serum total cholesterol, triglyceride (TG), low-density lipoprotein (LDL)
cholesterol, or apelin levels as well as waist-to-hip ratio (WHR) between the two groups.


Conclusion: Synbiotic supplementation improved glycemic indices, lipid profile and obesity values in women
with PCOS. These beneficial effects were not related with alterations in serum apelin levels (Registration number:
IRCT20100408003664N19).
کلیدواژه‌های انگلیسی مقاله Polycystic Ovary Syndrome, Synbiotic, Metabolic Factors, Obesity, Apelin
نویسندگان مقاله Sima Darvishi |
Student’s Research Committee, Department of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran

Maryam Rafraf |
Nutrition Research Center, Department of Community Nutrition, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran

Mohammad Asaghari Jafarabadi |
Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

Laya Farzadi |
Department of Obstetrics and Gynecology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

نشانی اینترنتی https://www.ijfs.ir/article_45901_9c7698805e925b3add62bfedff7e1da0.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات