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International Journal of Fertility and Sterility، جلد ۱۴، شماره ۳، صفحات ۲۶۲-۲۶۳

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عنوان انگلیسی COVID-19 Mediated by Basigin Can Affect Male and Female Fertility
چکیده انگلیسی مقاله Coronavirus disease 2019 (COVID-19) prevalence has caused many problems in society and disrupted many
regular aspects of life. COVID-19 contains major structural proteins that among them, S protein can promote
fusion of the viral and cellular membranes and facilitate the entry of coronavirus into the host cells. Basigin
(BSG) is one of the most important receptors for COVID-19 that mediates its entry to host cells. Also, Basigin
has an important role in male and female reproduction. Basigin is expressed in the uterus and plays an
important role during embryo implantation and needed for successful implantation. Therefore, disruption or
inhibition of Basigin causes to a weakness in embryo implantation. Therefore, if a woman or a man is infected
with COVID-19, it is recommended that they do not attempt to conception until their treatment is complete. It
is also recommended tests for COVID-19 be performed on infertile couples before using assisted reproductive
technology (ART).
کلیدواژه‌های انگلیسی مقاله Basigin, CD147, COVID-19, Fertility

نویسندگان مقاله Soodeh Mahdian |
Department of Cellular and Molecular Biology, Faculty of Biological Sciences, North Tehran Branch, Islamic Azad University, Tehran, Iran

Maryam Shahhoseini |
Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

Ashraf Moini |
Department of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran


نشانی اینترنتی https://www.ijfs.ir/article_45674_f571c3e965f0662181f09336570aec5a.pdf
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