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International Journal of Fertility and Sterility، جلد ۱۴، شماره ۱، صفحات ۳۴-۴۰
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عنوان انگلیسی Cumulative Live-Birth Rates by Maternal Age after One or Multiple In Vitro Fertilization Cycles: An Institutional Experience
چکیده انگلیسی مقاله Background
The aim of this retrospective study is to investigate the cumulative live birth rate (CLBR) following one or more completed in vitro fertilization (IVF) cycles (up to 6 cycles) stratified by maternal age and type of infertility.
Materials and Methods
In this retrospective study, five hundred forty-seven women who received 736 fresh ovarian stimulation/embryo transfer cycles between January 2016 and December 2016 were included in the study at a tertiary care center located in Lebanon.
Results
In all women, the live birth rate for the first cycle was 33.0% [95% confidence interval (CI): 27.8-38.2]. The CLBR showed an increase with each successive fresh cycle to reach 56.9% (95% CI: 51.2-62.4) after 3 cycles and 67.9% (95% CI: of 62.5-73.0) after 6 cycles. The CLBR following 6 cycles reached 69.9% (95% CI: 63.8-75.6) in women younger than 35 years. In women older than 40 years, however, the live birth rate for the first cycle was signifi- cantly low at 3.1% (95% CI: 0.3-9.5) with a plateau in success rates after 4 cycles reaching 21.9% (95% CI: 9.2-40.0). Couples with different types of infertility had CLBRs ranging from 65% to 72%, with the exception of women with low ovarian reserve, where CLBRs reached 29.4% (95% CI: 10.3-56.0).
Conclusion
The CLBR at a referral center in a Middle Eastern country reached 67.9 % after 6 cycles, with variations by age and type of infertility treatment. These findings are encouraging for patients insisting to extend their treatment beyond 4 to 5 cycles.
کلیدواژه‌های انگلیسی مقاله Assisted Reproductive Techniques, Live Birth Pregnancy Rate, Maternal Age, Multiple Pregnancy
نویسندگان مقاله Dalia Khalife |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

Anwar Nassar |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

Ali Khalil |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

Johnny Awwad |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

Antoine Abu Musa |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

Antoine Hannoun |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

Lina El Taha |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

Fatin Khalifeh |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

May Abiad |
Faculty of Medicine, American University of Beirut, Beirut, Lebanon

Ghina Ghazeeri |
Department of Obstetrics and Gynecology, American University of Beirut Medical Center, Beirut, Lebanon

نشانی اینترنتی https://www.ijfs.ir/article_45575_5f14987624e26c4469993e1ece2c7fe1.pdf
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