این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Fertility and Sterility، جلد ۱۲، شماره ۴، صفحات ۳۲۹-۳۳۴

عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله

عنوان انگلیسی Correlation of Maternal Stress Because of Positive Aneuploidy Screening Serum Analytes and Uterine Arteries’ Doppler Ultrasound Index: A Prospective Cohort Study
چکیده انگلیسی مقاله Background
Antenatal anxiety or maternal stress is a prevalent chronic mental disorder in pregnant women. We have assessed the effect of maternal stress from positive aneuploidy screening results on the changes in uterine artery blood flow.
Materials and Methods
We performed a prospective cohort (one sample) pilot study at a hospital in Tehran, Iran. A total of 60 pregnant women who were candidates for amniocentesis due to abnormal sequential screening test results entered the study. We conducted 2 standard psychological tests, the Spielberger’s State-Trait Anxiety Inventory and the Beck Anxiety Inventory, to determine anxiety levels in the participants before amniocentesis and two weeks after amniocentesis. The uterine artery resistance index was also measured before and two weeks after amniocentesis. The level of maternal stress was compared with the uterine artery resistance index.
Results
Patients had a mean State Trait Anxiety Inventory score before amniocentesis of greater than 40, which meant that the mothers experienced high anxiety. There were no correlations between both inventories’ anxiety scores and uterine artery blood flow before amniocentesis. However, two weeks after amniocentesis, we observed significant negative correlations between the State Anxiety (P=0.0041) and Trait Anxiety (P=0.010) Inventory scores and the uterine artery resistance indexes. Also, there was an association between the decreased right uterine artery resistance index and State Anxiety scores (P=0.036). There were significant correlations between State and Trait Anxiety scores and second trimester analytes of β-human chorionic gonadotropin (β-hCG, P < 0.001), α-fetoprotein (P < 0.001), and unconjugated estriol (P=0.048).
Conclusion
Maternal anxiety because of positive aneuploidy screening serum analytes and amniocentesis can af- fect perinatal outcomes via mood-based alterations in blood flow of the uterine arteries and the screening markers β-hCG,unconjugated estriol, and α-fetoprotein.
کلیدواژه‌های انگلیسی مقاله Amniocentesis, Doppler, Prenatal Screening, Stress Disorders, Uterine Artery

نویسندگان مقاله Mahboobeh Shirazi |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran

Parichehr Pooransari |
Shohada Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Fatemeh Rahimi Sharbaf |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran

Shirin Niromanesh |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran

Behrokh Sahebdel |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran

Mamak Shariat |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran

Zeinab Pahlavan |
Department of Perinatology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

Mahmoud Shirazi |
4Department of Psychology, University of Sistan and Baluchestan, Zahedan, Iran

Maryam Ahmadian |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran


نشانی اینترنتی https://www.ijfs.ir/article_45512_afca6b6aed9c856dfb7bfb432ceba644.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات