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JCR 2016
جستجوی مقالات
سه شنبه 2 دی 1404
International Journal of Fertility and Sterility
، جلد ۱۲، شماره ۴، صفحات ۳۲۹-۳۳۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Correlation of Maternal Stress Because of Positive Aneuploidy Screening Serum Analytes and Uterine Arteries’ Doppler Ultrasound Index: A Prospective Cohort Study
چکیده انگلیسی مقاله
Background
Antenatal anxiety or maternal stress is a prevalent chronic mental disorder in pregnant women. We have assessed the effect of maternal stress from positive aneuploidy screening results on the changes in uterine artery blood flow.
Materials and Methods
We performed a prospective cohort (one sample) pilot study at a hospital in Tehran, Iran. A total of 60 pregnant women who were candidates for amniocentesis due to abnormal sequential screening test results entered the study. We conducted 2 standard psychological tests, the Spielberger’s State-Trait Anxiety Inventory and the Beck Anxiety Inventory, to determine anxiety levels in the participants before amniocentesis and two weeks after amniocentesis. The uterine artery resistance index was also measured before and two weeks after amniocentesis. The level of maternal stress was compared with the uterine artery resistance index.
Results
Patients had a mean State Trait Anxiety Inventory score before amniocentesis of greater than 40, which meant that the mothers experienced high anxiety. There were no correlations between both inventories’ anxiety scores and uterine artery blood flow before amniocentesis. However, two weeks after amniocentesis, we observed significant negative correlations between the State Anxiety (P=0.0041) and Trait Anxiety (P=0.010) Inventory scores and the uterine artery resistance indexes. Also, there was an association between the decreased right uterine artery resistance index and State Anxiety scores (P=0.036). There were significant correlations between State and Trait Anxiety scores and second trimester analytes of β-human chorionic gonadotropin (β-hCG, P < 0.001), α-fetoprotein (P < 0.001), and unconjugated estriol (P=0.048).
Conclusion
Maternal anxiety because of positive aneuploidy screening serum analytes and amniocentesis can af- fect perinatal outcomes via mood-based alterations in blood flow of the uterine arteries and the screening markers β-hCG,unconjugated estriol, and α-fetoprotein.
کلیدواژههای انگلیسی مقاله
Amniocentesis, Doppler, Prenatal Screening, Stress Disorders, Uterine Artery
نویسندگان مقاله
Mahboobeh Shirazi |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
Parichehr Pooransari |
Shohada Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Fatemeh Rahimi Sharbaf |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
Shirin Niromanesh |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
Behrokh Sahebdel |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
Mamak Shariat |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
Zeinab Pahlavan |
Department of Perinatology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran
Mahmoud Shirazi |
4Department of Psychology, University of Sistan and Baluchestan, Zahedan, Iran
Maryam Ahmadian |
Maternal, Fetal and Neonatal Research Centre, Tehran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی
https://www.ijfs.ir/article_45512_afca6b6aed9c856dfb7bfb432ceba644.pdf
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