این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Fertility and Sterility، جلد ۸، شماره ۴، صفحات ۳۵۱-۳۶۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Association between Environmental Dioxin-Related Toxicants Exposure and Adverse Pregnancy Outcome: Systematic Review and Meta-Analysis
چکیده انگلیسی مقاله Dioxin-related compounds are associated with teratogenic and mutagenic risks in laboratory animals, and result in adverse pregnancy outcomes. However, there were inconsistent results in epidemiology studies. In view of this difference, we conducted a systematic review and meta-analysis to examine this association and to assess the heterogeneity among studies. Comprehensive literature searches were performed to search for relevant articles published in English up to 15 May 2012. In total, we identified 15 studies which included 9 cohort and 6 case control studies. The Cochrane Q test and index of heterogeneity (I2) were used to evaluate heterogeneity. In either cohort studies (I2=0.89, p < 0.0001) or case control studies (I2=0.69, p=0.02), significant heterogeneity of risk estimates were observed. Subgroup analyses found no significant increased risk of adverse pregnancy outcome with air dioxin-related compounds exposure (RR=0.99, 95% CI:0.85–1.16), no significant increased risk of spontaneous abortion (SAB) with exposure to food dioxin-related compounds (RR=1.05, 95% CI:0.80–1.37), higher significant risks of low birth weight (LBW) with exposure to food dioxin-related compounds (RR=1.55, 95% CI:1.24–1.94), and higher significant risks of birth defects with maternal solid contaminants dioxin exposure (OR=1.24, 95% CI:1.19–1.29). In conclusion, more evidences are needed to confirm the association between environmental dioxin-related compounds exposure and pregnancy outcome.
کلیدواژه‌های انگلیسی مقاله Dioxin, Pregnancy Outcome, Meta, Analysis
نویسندگان مقاله Xinjuan Pan |
College of Public Health, Zhengzhou University, Zhengzhou, China;Medical College, Henan University of Science and Technology, Luoyang, China

Xiaozhuan Liu |
College of Public Health, Zhengzhou University, Zhengzhou, China;Medical College, Henan University of Science and Technology, Luoyang, China

Xing Li |
College of Public Health, Zhengzhou University, Zhengzhou, China

Nannan Niu |
College of Public Health, Zhengzhou University, Zhengzhou, China

Xinjuan Yin |
College of Public Health, Zhengzhou University, Zhengzhou, China

Ning Li |
College of Public Health, Zhengzhou University, Zhengzhou, China

Zengli Yu |
College of Public Health, Zhengzhou University, Zhengzhou, China

نشانی اینترنتی https://www.ijfs.ir/article_45263_a3747e9f9f8f2a86d2e79a0a96a8bc2a.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات