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International Journal of Fertility and Sterility، جلد ۷، شماره ۳، صفحات ۲۰۷-۲۱۶
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عنوان انگلیسی Pregnancy Rate after First Intra Cytoplasmic Sperm Injection- In Vitro Fertilisation Cycle in Patients with Endometrioma with or without Deep Infiltrating Endometriosis
چکیده انگلیسی مقاله Background: To evaluate the impact of the association of endometrioma with or without deep infiltrating endometriosis (DIE) after a first intra cytoplasmic sperm injection- in vitro fertilization (ICSI-IVF) cycle on pregnancy rate. Materials and Methods: In this retrospective study, women with endometrioma who underwent a first ICSI-IVF cycle from January 2007 to June 2010 were reviewed for pregnancy rate. The main outcome measure was the clinical pregnancy rate. A multiple logistic regression (MLR) was performed; including all variables that were correlated to the conception rate. Only independent factors of pregnancy rate were included in a Recursive Partitioning (RP) model. Results: The study population consisted of 104 patients (37 without DIE and 67 patients with associated DIE). Using multivariable analysis, a lower pregnancy rate was associated with the presence of DIE (OR=0.24 (95% CI: 0.085-0.7); p=0.009) and the use of ICSI (OR=0.23 (95% CI: 0.07-0.8); p=0.02). A higher pregnancy rate was associated with an anti-mullerian hormone (AMH) serum level over 1 ng/ml (OR=4.3 (95% CI: 1.1-19); p=0.049). A RP was built to predict pregnancy rate with good calibration [ROC AUC (95% CI) of 0.70 (0.65-0.75)]. Conclusion: Our data support that DIE associated with endometrioma in infertile patients has a negative impact on pregnancy rate after first ICSI-IVF cycle. Furthermore, our predictive model gives couples better information about the likelihood of conceiving.
کلیدواژه‌های انگلیسی مقاله Endometrioma, Assisted Reproductive Technology, Endometriosis, Probabilistic Model
نویسندگان مقاله Anne Oppenheimer |
Department of Gynecology-Obstetrics, Tenon Hospital, GRC-UPMC 6 (C3E), Pierre et Marie Curie Paris 6 University, Paris, France

Marcos Ballester |
Department of Gynecology-Obstetrics, Tenon Hospital, GRC-UPMC 6 (C3E), Pierre et Marie Curie Paris 6 University, Paris, France

Emmanuelle Mathieu D’Argent |
Department of Gynecology-Obstetrics, Tenon Hospital, GRC-UPMC 6 (C3E), Pierre et Marie Curie Paris 6 University, Paris, France

Karine Morcel |
Department of Gynecology-Obstetrics, Rennes Hospital, Paris, France

Jean-Marie Antoine |
Department of Gynecology-Obstetrics, Tenon Hospital, GRC-UPMC 6 (C3E), Pierre et Marie Curie Paris 6 University, Paris, France

Emile Daraï |
Department of Gynecology-Obstetrics, Tenon Hospital, GRC-UPMC 6 (C3E), Pierre et Marie Curie Paris 6 University, Paris, France

نشانی اینترنتی https://www.ijfs.ir/article_45195_b76f23d3c16b70f40261ef578994bb34.pdf
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