این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
International Journal of Fertility and Sterility، جلد ۵، شماره ۲، صفحات ۵۴-۶۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Pathogenesis and Causes of Premature Ovarian Failure: An Update
چکیده انگلیسی مقاله Premature ovarian failure (POF) affects 1% of young women. This condition has significant psychological sequelae and major health implications. POF seriously interferes with fertility and family planning. Diverse etiologies are associated with POF. Literature review related to the causes and pathogenesis of POF, cited between the year 1900 and May 2010. POF may be either spontaneous or induced. The known causes include: Genetic disorders, which could involve the X chromosome or autosomes. However, the growing body of literature demonstrates a list of newly discovered mutations that may be responsible for causing POF. Most of these mutations are extremely rare, and most cases of POF are still considered to be idiopathic. Autoimmune causes; there is some evidence of an association of POF with lymphocytic oophoritis and other autoimmune disorders. Antiovarian antibodies are reported in POF, but their specificity and pathogenic role are obscure. Iatrogenic causes; chemotherapy, radiotherapy and pelvic surgery can lead to POF. Infectious Causes; some viral and microbial infections can be followed by POF. Environmental toxins, such as cigarette smoking are reported as risk factors of spontaneous POF. Idiopathic; in most cases, no identifiable etiology can be recognized after complete evaluation.
کلیدواژه‌های انگلیسی مقاله Premature Menopause, Premature Ovarian Failure, Hypergonadotropic Ovarian Failure, Hypergonadotropic Hypogonadism, Premature Ovarian Insufficiency
نویسندگان مقاله Mahbod Ebrahimi |
Obstetrics and Gynecology Department, Women’s (Mirza Koochak Khan) Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran;Obstetrics and Gynecology Department, Faculty of Medicine

Firoozeh Akbari Asbagh |
Obstetrics and Gynecology Department, Women’s (Mirza Koochak Khan) Hospital, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran

نشانی اینترنتی https://www.ijfs.ir/article_45084_dce8e8747adb488ce7bc16a49a5c0091.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات