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Iranian Heart Journal، جلد ۲۳، شماره ۱، صفحات ۱۹۸-۲۰۴
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عنوان انگلیسی Cardiac Troponin Variation Trends in Patients With Acute Pulmonary Embolism
چکیده انگلیسی مقاله Background: Pulmonary embolism (PE) is among the deadliest diseases in that it can cause sudden death. The present study aimed to determine cardiac troponin I (CTnI) variation trends in patients with acute PE referred to Rajaie Cardiovascular Medical and Research Center.   Methods: This cross-sectional descriptive-analytical study consecutively enrolled 54 patients with acute PE. Variation trends of CTnI were measured in the study population at 5 different time points: upon admission and subsequently 8, 24, 48, and 72 hours post-admission. The relationships between CTnI variation trends and computed tomography angiography, echocardiography, and electrocardiography findings were investigated. CTnI variation trends were compared between a group undergoing catheter-directed thrombolysis (CDT) and a group receiving the conventional anticoagulant treatment. The data were analyzed using the SPSS software, version 20.   Results: A reduction was observed in the CTnI variation trends of all the samples. Both groups exhibited a decline in CTnI levels, but the slope of this reduction was steeper in the CDT group (P=0.04). Additionally, a significant relationship was also detected between CTnI reduction and right ventricular function improvement (P=0.04). No significant association was observed between systolic pulmonary artery pressure changes and CTnI variation trends.   Conclusions: The results indicated a significant relationship between reduced CTnI levels and improved right ventricular function. Additionally, the CDT group showed a significant fall in the CTnI level compared with the anticoagulant-only group. (Iranian Heart Journal 2022; 23(1): 198-204)
کلیدواژه‌های انگلیسی مقاله pulmonary thromboembolism,Anticoagulant,Cardiac troponin I
نویسندگان مقاله Mohammad Mehdi Peighambari |
Cardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.

Mohammad Javad Alemzadeh-Ansari |
Cardiovascular Intervention Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.

Golnoush Yaghoubzadeh |
Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.

Sepideh Masteri Farahani |
Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.

نشانی اینترنتی http://journal.iha.org.ir/article_142614_b0b1709f0d6db2bd11b31abf8d53f396.pdf
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