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Tanaffos، جلد ۱۹، شماره ۲، صفحات ۱۱۲-۱۲۱

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عنوان انگلیسی Real Clinical Practice and Therapeutic Management Following COVID-19 Crisis in two Hospitals in Iran: A Statistical and Conceptual View
چکیده انگلیسی مقاله Background: The Coronavirus disease 2019 (COVID-19) outbreak quickly has spread and became a pandemic. However, no approved therapeutics or effective treatment is available for the treatment of these patients. The present study was done to retrospectively assess the treatment strategies (e.g., pharmaceutical care services) for COVID-19 patients in selected hospitals and highlight the importance of such services in the management of a pandemic.
Materials and Methods: Data from a series of COVID-19 patients (978 patients; 658 males [66.9%] and 324 females [33.1%]) admitted to the selected hospitals in Tehran from 20 February to 19 March 2020 were retrieved retrospectively from the Health Information System (HIS) of the hospitals. The statistical tests were used for analyzing the effect and correlation of the variables (drugs) with the average length of stay (ALOS) in the hospital.
Results: Diverse medication classes and old drugs with or without strong evidence of therapeutic effects against the novel coronavirus, some previously tried as a treatment for SARS-CoV and MERS-CoV, were mostly used for the treatment of patients in the hospitals. Many medications (broad-spectrum antibiotics and antivirals) or combination therapies are used without evidence of their therapeutic effects during pandemics.
Conclusion: Therefore, guidelines should be provided for the off-label use of these drugs by policymakers and stakeholders during a pandemic emergency due to high demands. Also, monitoring of the HIS data can play an important role in improving public health response to emerging diseases.
کلیدواژه‌های انگلیسی مقاله COVID-19,Treatment Strategies,Hospital Information System (HIS)

نویسندگان مقاله Ali Najafi |
Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran,

Mostafa Ghanei |
Chemical Injuries Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran,

Ghasem Janbabaei |
Department of Hematology Oncology, Tehran University of Medical Sciences, Tehran, Iran,

Ali Akbar Velayati |
Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Seyed Hassan Saadat |
Behavioral Sciences Research Center, Lifestyle Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran,

Hamidreza Jamaati |
Chronic Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Payam Tabarsi |
Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Farzaneh Dastan |
Chronic Respiratory Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Malihe Ram |
Department of Biostatistics, Ferdows Paramedical School, Birjand University of Medical Sciences, Birjand, Iran,

Enayat Darabi |
School of Public Health, Tehran University of Medical Sciences, Tehran, Iran,

Saeid Fathi |
Postdoctoral Fellow, University of Tehran, Tehran, Iran,

Mohammad Gholami Fesharaki |
Biostatistics Department, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran,

Amir Hosein Ghazale |
Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Shahrzad Saloo |
Student Research Committee, Baqiyatallah University of Medical Sciences, Tehran, Iran.


نشانی اینترنتی https://www.tanaffosjournal.ir/article_239705_94cc38e713745862617d908e71fddd98.pdf
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