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Tanaffos، جلد ۱۵، شماره ۴، صفحات ۲۱۳-۲۱۷
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عنوان انگلیسی Role of Transcranial Doppler Sonography in Diagnosis of Brain Death: A Single Center Study
چکیده انگلیسی مقاله Background: Diagnosis of brain death relies on clinical and electroencephalographic (EEG) criteria. Waiting for 24 hours is mandatory to make definitive diagnosis of the condition in the Iranian protocol. Although it has been previously shown that oscillatory or spiked systolic or reversed diastolic flow patterns in transcranial Doppler sonography (TCD) are associated with faster brain death confirmation, it has not yet been approved in our protocol. Thus, the aim of this study was to assess the applicability of this method to our organ donation system. Materials and Methods: This study was performed in Masih Daneshvari Organ Procurement Unit from July to December 2009. TCD from the middle cerebral and basilar arteries was attempted in 35 patients who fulfilled the clinical and EEG criteria for brain death. Extensive skull defects and hypotension (blood pressure < 80 mmHg) were the exclusion criteria. Examinations were made for about 30 minutes via temporal and occipital windows as soon as possible after diagnosis of brain death. Results: The mean age of cases was 31.9±14.78 years and 18 (51.4%) were males. The most prevalent cause of brain death was trauma (in 19 or 54.2% of cases). We were unable to detect any intracranial artery in 2 (5.7%) cases. There were no false negative or false positive results in the remaining ones. Detected ultrasonic patterns of cerebral vascular flow were systolic spike and oscillating signal in 29 (87.9%) and 4 (12.1%) donors, respectively. Conclusion: Our study showed that TCD results in brain dead cases were concordant with clinical and EEG criteria. Therefore, TCD, as a confirmatory test, can be applied for rapid diagnosis of brain death.
کلیدواژه‌های انگلیسی مقاله Brain death,Transcranial Doppler Sonography,Electroencephalography
نویسندگان مقاله Seyed Mohammadreza Hashemian |
Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Hosein Delavarkasmaei |
Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Katayoun Najafizadeh |
Lung Transplantation Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Meysam Mojtabae |
Lung Transplantation Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Seyed Hossein Ardehali |
Department of Critical Care, Shohadaye-Tajrish Hospital, Shahid Beheshti University of Medical Sciences,

Mohammad Reza Kamranmanesh |
Department of Anesthesiology & Critical Care and Pain Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Niloofar Basharzad |
Department of Pulmonology and Intensive Care Medicine, Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran,

Fariba Ghorbani |
Tracheal Diseases Research Center, NRITLD, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mohammad Reza Kamranmanesh |
Department of Anesthesiology & Critical Care and Pain Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran,

نشانی اینترنتی https://www.tanaffosjournal.ir/article_240207_858394c879eb5cd09c670a22850fef28.pdf
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