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Tanaffos، جلد ۸، شماره ۳(summer)، صفحات ۲۸-۳۶
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عنوان انگلیسی A Clinicopathologic Study of Lung Cancer Cases in Iran
چکیده انگلیسی مقاله Background: Lung cancer remains the leading cause of cancer-related deaths in the world. In Iran, lung cancer is the fifth leading cancer and its prevalence rate has been increasing steadily. In this study, the clinicopathological aspects of lung cancer are discussed. Materials and Methods: Between October 2002 and November 2005, 242 (178 men, 64 women) patients with histologically confirmed lung cancer were interviewed according to a questionnaire. Results: Women developed the disease at an earlier age than men (55.9±14.2 versus 61.3±12.3 years; p=0.004); 66.5% of lung cancer patients (85.4% of men and 14.1% of women) were smokers (p <0.0001); 76.3% of participants, who had exposure to secondhand smoke, were females. Among the environmental carcinogens, the most exposures were to inorganic dusts (49.8%) and chemical compounds (34.9%).Most male and female patients suffered from adenocarcinoma (28.9%) and non small cell carcinoma (28.5%). The prevalence of adenocarcinoma was higher in the non-smoker group, whereas incidence of squamous cell carcinoma and small cell carcinoma was higher among smokers (p <0.0001). In this study, most patients (74.0%) presented with an advanced-stage tumor (IIIB or IV). Conclusion: Our results suggest that in addition to cigarette smoking, other environmental, occupational and socioeconomic factors may play a role in the development of lung cancer. (Tanaffos 2009; 8(3): 28-36)
کلیدواژه‌های انگلیسی مقاله Lung cancer,Smoking,Exposure,Histology
نویسندگان مقاله Parisa Adimi Naghan |
Department of Pulmonary Medicine

Mostafa Hosseini |
Department of Epidemiology and Biostatistics, School of Public Health,

Seyed Ahmad Seyed Alinaghi |
Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences,

Shirin Karimi |
Department of Clinical Anatomical Pathology

Moslem Bahadori |
Department of Clinical Anatomical Pathology

Kian Khodadad |
Chronic Respiratory Disease Research Center

Forozan Mohammadi |
Department of Clinical Anatomical Pathology

Kaveh Keynama |
Department of Pulmonary Medicine

Laleh Rahmani |
Department of Pulmonary Medicine

Mohammad Reza Masjedi |
Department of Pulmonary Medicine

نشانی اینترنتی https://www.tanaffosjournal.ir/article_241210_7955926b0aa21d065f5248d09a50738b.pdf
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