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Iranian Journal of Pathology، جلد ۱۷، شماره ۴، صفحات ۴۷۷-۴۸۱
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عنوان انگلیسی A Rare Case of Cardiac Metastasis from Colon Cancer
چکیده انگلیسی مقاله It is very rare for colorectal neoplasms to metastasize to the heart in the worldwide medical literature; only a single case of well-documented colorectal cancer metastasis to the left atrium was found. The case of a 66-year-old man is explained in this paper, who was suffering from metastatic adenocarcinoma of the colon that included the left atrium. In transthoracic and transesophageal echocardiography, a large multilobulated mass was present in the left atrium. An accidental pulmonary mass was also seen in a lung spiral CT scan. The cardiac mass was taken out, and a biopsy was obtained from the pulmonary mass. Adenocarcinoma was seen in histological assessment. Immunohistochemical staining was carried out to examine the expression of cytokeratin 7, cytokeratin 20, and caudal-related homeobox transcription factor 2 (CDX2) to determine the origin of the adenocarcinoma. In addition, the expression of these proteins was linked to the attributes of the patient and tumor. Post-surgery transesophageal echocardiography showed normal left ventricle and right ventricle function with no evidence of left atrium mass. Therefore, we suggest that asymptomatic cancer patients with a history of colorectal cancer and who have developed cardiac symptoms should be immediately examined for potential cardiac metastasis.
کلیدواژه‌های انگلیسی مقاله Cardiac metastasis,Colorectal Neoplasms,Heart,Left atrium,Metastatic adenocarcinoma
نویسندگان مقاله Zahra Modabber |
Student Committee Research, Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

Roghayeh Pourkia |
Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

Hamidreza Vafaey |
Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

Ali Alizadeh |
Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

Mohammad Ranaei |
Cellular and Molecular Biology Research Center, Health Research Institute, Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran

نشانی اینترنتی https://ijp.iranpath.org/article_254804_95ef90d4eaa4299a4698b6c75672d261.pdf
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