این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Pathology، جلد ۱۷، شماره ۱، صفحات ۸-۱۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Higher Viral Load of Polyomavirus Type BK but not JC among Renal Transplant Recipients in Comparison to Donors
چکیده انگلیسی مقاله Background & Objective: Polyomaviruses types BK and JC and Cytomegalovirus (CMV) have been shown to be related to kidney transplantation complications. This study aimed to assess the prevalence of these viruses in patients receiving kidney transplantation.
Methods: This cross-sectional study was performed on 40 kidney transplant recipients and 44 donors. Urine samples were used for the extraction of viral DNA. The prevalence of JC and BK viruses and their viral loads were determined by real-time polymerase chain reaction.
Results: JC and BK viruses were identified in 31% and 92.3% of all subjects, respectively. The frequency of JC and BK cases was not statistically different between the recipient and donor groups (P>0.05). All patients in the donor group and 96.8% of the recipients were positive for CMV IgG antibody. The mean viral load of BK in donors and recipients was 4.5×1010 and 3.3×1011 copies, respectively. The mean viral load of JC was 8.6×107 copies in donors and 2.9×108 copies in recipients. The distribution of BKV was significantly higher in recipients than donors (P=0.001), while no difference was observed between the two studied groups for JCV.
Conclusion: This study showed a relatively high prevalence of BK and JC viruria in both renal transplant donors and recipients. The viral load for BKV, but not JCV, was higher in recipients than in donors.
کلیدواژه‌های انگلیسی مقاله BK virus,Cytomegalovirus,JC virus,Renal transplant
نویسندگان مقاله Samaneh Abolbashari |
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

MohammadTaghi Shakeri |
Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Maryam Hami |
Kidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Aida Gholoobi |
Medical Genetics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Amin Hooshyar Chechaklou |
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Mohammad Sadegh Damavandi |
Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Aref Movaqar |
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Razieh Yousefi |
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

Zahra Meshkat |
Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Saeedeh Hajebi Khaniki |
Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

نشانی اینترنتی https://ijp.iranpath.org/article_248526_02887062b83065c97cc918ec613805af.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات