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Iranian Journal of Pathology، جلد ۱۶، شماره ۱، صفحات ۸۴-۸۹
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عنوان انگلیسی Gliosarcoma with Adenoid and Chondrosarcomatous Differentiation: A Case Report
چکیده انگلیسی مقاله A heterogeneous group of CNS tumors are characterized by mixed neuroepithelial and mesenchymal features. Glial tumors manifesting this phenomenon are referred to as gliosarcoma. These tumors are usually mistaken for cerebral metastases or meningioma at operation. Their histological studies have revealed an admixture of gliomatous and sarcomatous tissues, which leads to a biphasic pattern. The mesenchymal component can present in different forms such as fibrosarcoma, undifferentiated pleomorphic sarcoma, chondro-osteogenic, and myogenic differentiation, as well as angiosarcomatous and liposarcomatous types. Squamous differentiation, adenoid formations and glandular structures may also be displayed.
Herein, we report a rare case who was admitted to the emergency room with decreased consciousness resembling methadone poisoning. Clinical work-up showed a temporoparietal mass on radiological investigation. Histopathological evaluation of the brain mass revealed a gliosarcoma with adenoid formations and a mesenchymal component, which manifested as chondrosarcomatous differentiation. Immunohistochemical studies confirmed the histologic diagnosis through positivity for EMA, GFAP, S100, and vimentin expression in different components.
کلیدواژه‌های انگلیسی مقاله Adenoid Differentiation,Chondrosarcomatous Differentiation,Gliosarcoma
نویسندگان مقاله Elham Jafari |
Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran

Shiva Didehban |
Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran

Shahriar Dabiri |
Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran

Behshad Mofid |
Clinical Research Unit, Shahid Bahonar Academic Center, Kerman University of Medical Sciences, Kerman, Iran

نشانی اینترنتی https://ijp.iranpath.org/article_46932_91dc58d90640f930f98d6e4eefd6fd2c.pdf
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