این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Research Journal of Pharmacognosy، جلد ۱۰، شماره ۱، صفحات ۱۵-۲۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Fennel-Lemon Balm Syrup for Alleviating Hot Flash in Post-Menopausal Women, a Pilot Study
چکیده انگلیسی مقاله Background and objectives: Hot flash is one of the most common problems in post-menopausal women. The usual treatment is hormone therapy with estrogen and progesterone, which presents side effects such as heart attack, cancer, and depression. In Iranian traditional medicine, some prescriptions have been recommended for treatment of hot flash; in the present study, a syrup was formulated based on traditional medicine and the efficacy in hot flash was evaluated in a pilot study in post-menopausal women. Methods: Foeniculum vulgare (fennel) and Melissa officinalis (lemon balm) were used for preparing the syrup. Physicochemical and microbial quality control tests were performed and the syrup was standardized based on rosmarinic acid and total phenolics content. The effect in post-menopausal women was evaluated in a pilot study with Carpenter Hot Flash Related Daily Interference Scale questionnaire. Results: The results of the quality control and accelerated stability tests after six months were in agreement with the acceptance criteria. The pH, density, viscosity, dry residue, total phenolics and rosmarinic acid contents were 5.29, 1.12 g/cm3, 42.15 cP, 43.43, 4 mg/mL (as pyrogallol) and 1.28 mg/mL, respectively. In the pilot study, the number and intensity of hot flash decreased (p<0.05); however, there were no significant differences between the number and intensity of night sweating before and after the intervention (p>0.05). Conclusion: Considering the promising effect of the formulated syrup on hot flash and the acceptable quality and stability of the product, it can be suggested in larger clinical trials for confirming the efficacy.
کلیدواژه‌های انگلیسی مقاله Foeniculum vulgare,Hot flash,HPLC,Melissa officinalis,menopause
نویسندگان مقاله Mojgan Tansaz |
Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Najmeh Faridi |
Midwifery Department, Medical School, Arak University of Medical Sciences, Arak, Iran.

Homa Hajimehdipoor |
Traditional Medicine and Materia Medica Research Center and Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Leila Ara |
Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Behnaz Keramatian |
Traditional Medicine and Materia Medica Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Maryam Hamzeloo-Moghadam |
Traditional Medicine and Materia Medica Research Center and Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

نشانی اینترنتی http://www.rjpharmacognosy.ir/article_158072_fe92e77c3439d7dcbc783c743775ee3f.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات