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Research Journal of Pharmacognosy، جلد ۷، شماره ۴، صفحات ۱۱-۲۲
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عنوان انگلیسی Comparing the Effects of a Herbal Ointment (Based on Persian Medicine) and Silver Sulfadiazine Ointment on the Second-Degree Burn Wounds: a Single-Blind Randomized Clinical Trial
چکیده انگلیسی مقاله Background and Objective: Burn injuries impose heavy costs on the healthcare systems. Since the available treatments for burn injuries are costly and have several complications, the present study aimed to compare the effects of an Iranian traditional medicine product in the form of a herbal ointment with silver sulfadiazine ointment on second-degree burn wounds. Methods: In this single-blind randomized clinical trial, the patients were divided into two groups of herbal ointment (Rosa damascena, Solanum nigrum, and Malva sylvestris) and SSD ointment (control). They were evaluated in terms of improvement, wound closure, wound appearance, and intervention complications prior to the treatment, on the fourth day, and after 1-4 weeks. Results: Fifty three participants completed the trial (27 in herbal ointment and 26 in SSD group). The mean burn wound healing time was 11.58±5.36 and 16.80±5.60 days in the herbal and SSD groups, respectively, which showed a significant difference in this regard (p=0.001). Moreover, the wound closure percentage in the first two weeks was significantly higher in the herbal group compared to the SSD group (p <0.05). Also, wound appearance was better in the herbal ointment group in all the assessment times. No significant difference was observed between the herbal and SSD ointment regarding the treatment complications. Conclusion: The herbal ointment containing Rosa damascena, Malva sylvestris, and Solanum nigrum showed more considerable effects on the second-degree burn wounds compared to the SSD ointment.
کلیدواژه‌های انگلیسی مقاله Burns,Herbal medicine,silver sulfadiazine,traditional medicine
نویسندگان مقاله Mehdi Alizadeh |
Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mostafa Dahmardehei |
Burn Research Center, Iran University of Medical Sciences, Tehran, Iran.

Shirin Fahimi |
Traditional Medicine and Materia Medica Research Center and Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Sajjad Sadeghi |
Iranian Traditional Medicine Clinic, Amiralmomenin Hospital, Semnan University of Medical Sciences, Semnan, Iran.

Roshanak Mokaberinejad |
Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. No.8 Shams Alley, Vali-e-Asr Street, Tehran, Iran.

نشانی اینترنتی http://www.rjpharmacognosy.ir/article_111422_70fca2c2ef9f62cd686a08243ca5434f.pdf
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