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Analytical and Bioanalytical Electrochemistry، جلد ۱۴، شماره ۱، صفحات ۱۸-۳۱

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عنوان انگلیسی Simultaneous Electrochemical Analysis of Ibuprofen and Paracetamol by Clay Modified Carbon Paste Electrode: Analytical Application in Human Blood
چکیده انگلیسی مقاله Cyclic voltammetry and differential pulse voltammetry techniques for the simultaneous analysis of ibuprofen (IBU) and paracetamol (PCT) at carbon paste electrode modified with clay (CPE-Clay) are reported. The surface characterization of the clay was realized by zero-point charge and electrochemical methods. The electrocatalytic activity of clay toward ibuprofen electro-oxidation and paracetamol redox were reported. The kinetic parameters for ibuprofen and paracetamol electro-analysis by the modified carbon paste electrode clay-CPE were calculated. Peak ibuprofen oxidation and peaks paracetamol redox were well presented onto modified electrode clay-CPE when compared with other electrodes in the literature.  Peak oxidation of the ibuprofen and peaks paracetamol redox was well presented onto modified electrode clay-CPE compared with other electrodes in the literature. The high sensitivity of the clay-CPE is measured by the DPV method showed linear variation with ibuprofen and paracetamol concentration with respectively detection limit (LOD) of 3.23×10-8 mol L-1 and 1.04×10-8 mol L-1. The applicability of the working electrode has been explored by the simultaneous electroanalysis of the ibuprofen and paracetamol in human blood samples.
کلیدواژه‌های انگلیسی مقاله Clay,Electrochemical behaviour,Ibuprofen,Paracetamol,Electroanalysis,Human blood

نویسندگان مقاله EL Ouafy Hayat |
Laboratory of Engineering in Chemistry and Physics of Matter, Department of Chemistry and Environment, Faculty of Sciences and Technics, Sultan Moulay Slimane University, Beni Mellal, Morocco

Mouna Aamor |
Laboratory of Engineering in Chemistry and Physics of Matter, Department of Chemistry and Environment, Faculty of Sciences and Technics, Sultan Moulay Slimane University, Beni Mellal, Morocco

Oubenali Mustapha |
Laboratory of Engineering in Chemistry and Physics of Matter, Department of Chemistry and Environment, Faculty of Sciences and Technics, Sultan Moulay Slimane University, Beni Mellal, Morocco

Mbarki Mohamed |
Laboratory of Engineering in Chemistry and Physics of Matter, Department of Chemistry and Environment, Faculty of Sciences and Technics, Sultan Moulay Slimane University, Beni Mellal, Morocco

Aziz EL Haimouti |
Laboratory of Engineering in Chemistry and Physics of Matter, Department of Physics and Chemistry, Polydisciplinary Faculty of Khouribga, Sultan Moulay Slimane University, Beni Mellal, Morocco

EL Ouafy Tarik |
Laboratory of Engineering in Chemistry and Physics of Matter, Department of Physics and Chemistry, Polydisciplinary Faculty of Khouribga, Sultan Moulay Slimane University, Beni Mellal, Morocco


نشانی اینترنتی https://www.abechem.com/article_249319_932746832b10e48b741ad04cfc8e59cc.pdf
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