این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Analytical and Bioanalytical Electrochemistry، جلد ۱۳، شماره ۲، صفحات ۲۸۳-۲۹۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Electrochemical Behavior of Aminoguanidine and its Detection by Hybrid Polymer of Theophylline with Copper Oxide Nanoparticles
چکیده انگلیسی مقاله Aminoguanidine (AG), as a group of nucleophilic hydrazine compounds, has different pharmacological activities, like reducing the pathological consequence of diabetes. Here, the electrochemical oxidation behavior of aminoguanidine was examined, directly at bare graphite electrode and indirectly, with theophylline hybrid polymer and copper oxide nanoparticles, using cyclic voltammetry (CV) and square wave voltammetry (SWV). The impact of pH, buffer type, time, and concentration were studied in the two methods. Two oxidation peaks were found at (0.773 V , 1.15 V) vs. Ag/AgCl in acetate buffer (0.1 M, pH 4.5) and (0.8 V , 1.1 V) vs. Ag/AgCl in phosphate buffer (0.1 M, pH 7.0). At graphite bare electrode (GCE), the optimal result was achieved when the phosphate buffer was used, changing the linear range for the detection of aminoguanidine at bare electrode from 299.1 to 990 µM with R2 of 0.992 and standard deviation of 33.5 µM. At modified graphite electrode with theophylline hybrid polymer and copper oxide nanoparticles (GCE-poly TP/CuO-NPs), a much wider range was obtained for AG, at 9.9 to 610.316 µM with R2 =0.990 the limit of detection of 6.34 µM, and SD of 0.089 µM.
Finally, the preparation of modified graphite electrode with nanoparticles (GCE-poly TP/CuO NPs) showed good stability, persisting for more than 2 weeks, and showing a potential to be used as a drug sensor.
کلیدواژه‌های انگلیسی مقاله Aminoguanidine,CuO nanoparticles,Theophylline,Electropolymerization,Graphite electrode
نویسندگان مقاله Amer Th Al-Taee |
College of Science, University of Mosul, Department of Chemistry, Iraq

ALAA MT Al-Layla |
College of Science, University of Mosul, Department of Chemistry, Iraq

Anfal Raad Mahmood |
College of Science, University of Mosul, Department of Chemistry, Iraq

نشانی اینترنتی https://www.abechem.com/article_246479_a7bb1c8a39ff7a74701aedd1681524e4.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات