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International Journal of Nanoscience and Nanotechnology (IJNN)، جلد ۱۹، شماره ۴، صفحات ۲۰۹-۲۳۵
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عنوان انگلیسی Development of FDA-Approved Antibacterial Metal and Metal Oxide Nanoparticles: An Update
چکیده انگلیسی مقاله    Nanotechnology is an emerging discipline for biomedical application. Nanoparticles (NPs) research is one of the most studied and rapidly evolving field with its wide range of diagnostic and therapeutic applications, particularly in antimicrobial development. Following the improvement of the biomaterial’s functionality, the new area of ‘nanocomposites’ which often refers to the combination of NPs with other biomaterials such as hydrogel, polymers or other stabilizers, has swiftly followed. In the past decades, bacterial infections have caused negative impacts on human health, social and economic development in the globe. These problems are further aggravated by antibiotic resistance issues caused by drug-resistant microbes. With this, the development of antibacterial NPs has become an important field to alternate for the discovery of novel antibacterial agent. This review aims to discuss the key features of NPs, primarily derived from metal and metal oxide, for their antibacterial use in the clinic, the mechanisms of bacterial killing, and to cover some of the key challenges towards the Food and Drug Administration (FDA) approval for clinical use.
کلیدواژه‌های انگلیسی مقاله Drug,Antibacterial,nanoparticles,Metal,Metal oxide
نویسندگان مقاله Bri Anna |
Department of Medical Sciences, School of Medical and Life Sciences, Sunway University, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia

Bibi Noorheen Haleema Mooneerah Neerooa |
Department of Biological Sciences, School of Medical and Life Sciences, Sunway University, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia

Yongjing Hu |
Department of Biology, College of Science, Mathematics and Technology, Wenzhou-Kean University, 88 Daxue Road, Quhai, Wenzhou 325060, Zhejiang Province, China

Li-Ting Ooi |
School of Health Sciences, International Medical University, Bukit Jalil, 57100 Kuala Lumpur, Kuala Lumpur, Malaysia

Kamyar Shameli |
School of Medicine, Institute of Virology, Technical University of Munich, Munich, Germany

Jactty Chew |
Department of Medical Sciences, School of Medical and Life Sciences, Sunway University, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia

Sin-Yeang Teow |
Department of Biology, College of Science, Mathematics and Technology, Wenzhou-Kean University, 88 Daxue Road, Quhai, Wenzhou 325060, Zhejiang Province, China

نشانی اینترنتی https://www.ijnnonline.net/article_709101_f7bf3795054f9449fd8193b41864b9e9.pdf
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