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Iranian Journal of Chemistry and Chemical Engineering، جلد ۴۱، شماره ۹، صفحات ۲۹۴۶-۲۹۶۰

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عنوان انگلیسی Spectral and Electrochemical Sensing Studies of Novel Tetradentate Schiff Bases, Having Enhanced Antifungal Activity, Containing Ferrocene and Aromatic Moieties Attached Imines
چکیده انگلیسی مقاله Multi metal ion sensing unsymmetrical Schiff bases containing ferrocene group attached imine at one side and aromatic moiety connected azomethine on the other side have been synthesized. Titration studies coupled with a UV-Visible spectrophotometer expose the binding aptitude of new receptors. Development of MLCT band near 457 nm for the coordination of Cu2+ ions with new ligands is also noticed. Electrochemical studies of receptor solutions with added metal ions expose quasi-reversible processes by giving superfluous ΔEP values (146-161 mV, then the expected 59 mV). The concentration of metal ions required for effective sensing is calculated from the percentage amount of ΔIpa extracted from the Ipa data. Results obtained in computational molecular docking studies and in-vitro analysis invite more focused research by the pharmacist to develop new formulations for antifungal medicines.
کلیدواژه‌های انگلیسی مقاله Antifungal Compound,Binding Attitude,Cation Sensors,In-vitro,Molecular Docking

نویسندگان مقاله Kamatchi Selvaraj Ponnurangam |
PG & Research Department of Chemistry, Government Arts College for Men (Autonomous), Nandanam, Chennai-600 035, Tamil Nadu, INDIA

Selvaraj Shunmugaperumal |
PG & Research Department of Chemistry, Government Arts College for Men (Autonomous), Nandanam, Chennai-600 035, Tamil Nadu, INDIA

Saranya Dhasarathan |
PG & Research Department of Chemistry, Government Arts College for Men (Autonomous), Nandanam, Chennai-600 035, Tamil Nadu, INDIA


نشانی اینترنتی https://ijcce.ac.ir/article_247363_6191ee9ee03d113d00a898cbbdb62f52.pdf
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