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Veterinary Research Forum، جلد ۱۲، شماره ۳، صفحات ۳۸۳-۳۸۶
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عنوان انگلیسی Effect of medetomidine on left ventricular outflow tract velocity in cats: A Doppler echocardiography study
چکیده انگلیسی مقاله The purpose of the present study was to evaluate effects of medetomidine on left ventricular outflow tract (LVOT) velocity in domestic short-haired cats. Eighteen healthy adult male domestic short-haired cats were used for this study. All animals were client-owned. Echocardiography machine with 7.50 MHz transducer was used. Specific veterinary two-dimensional and pulse-waved echocardiogram images in apical five chamber right parasternal view were obtained and blood velocity in LVOT was calculated. After baseline echocardiographic recordings, 0.04 mg kg-1 of medetomidine was intramuscularly administered to each animal and LVOT velocity was calculated after 15 (T15), 50 (T30) and 80 (T80) min following drug administration. The LVOT velocity values (mean ± SEM) of cats in baseline were 1.06 ± 0.04 m sec-1. There were significant differences between baseline and T15 and T30 regarding mean LVOT values. Age and weight had no significant effect on LVOT velocity values. The LVOT velocity values of T15, T50 and T80 were 0.77 ± 0.04, 0.80 ± 0.02 and 0.96±0.03 m sec-1, respectively. Our findings revealed significant decrease in mean LVOT velocity up to 50 min following medetomidine administration. The present study determined normal LVOT velocity range for a small population of cats before and after intra-muscular medetomidine administration.
کلیدواژه‌های انگلیسی مقاله Cat,Left ventiricular outflow tract,Medetomidine
نویسندگان مقاله Reza Sadjadi |
Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, ‎ Tehran, Iran‎

Mohammad Nasrollahzadeh Masouleh |
Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, ‎ Tehran, Iran‎

Ahmad Asghari |
Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, ‎ Tehran, Iran‎

Saied Bokaie |
Department of Epidemiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

نشانی اینترنتی https://vrf.iranjournals.ir/article_243073_b880ef18497f1d74dfe1da4b20637562.pdf
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