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جستجوی مقالات
سه شنبه 25 آذر 1404
Veterinary Research Forum
، جلد ۱۲، شماره ۱، صفحات ۷-۱۳
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Protective effects of Citrullus lanatus seed ethanol extract on aluminum chloride-induced testosterone, testicular and hematological changes in an experimental male rat model
چکیده انگلیسی مقاله
The study was done to ascertain the protective potentials of ethanol seed extract of
Citrullus lanatus
on aluminum chloride-induced reproductive and hematological toxicities. Thirty mature male rats were used for the study. They were assigned into five groups (n=6). Group1was treated daily with aluminum chloride (100 mg kg
-1
)
per os
for 8 weeks. Group 2 was treated with aluminum chloride (100 mg kg
-1
) and
C. lanatus
seed extract (CLSE) 200 mg kg
-1
per os
simultaneously for 8 weeks. Group 3 was served as a normal control and given distilled water as a placebo
per os
daily for 8 weeks. Group 4 was only treated with CLSE (200mg kg
-1
) for eight weeks. Group 5 was only treated with aluminum chloride (100 mg kg
-1
)
per os
for 8 weeks and then treated with CLSE (200 mg kg
-1
)
per os
for another 4 weeks. Testosterone level, testicular weight, sperm motility, gonadal sperm, and extragonadal sperm reserves showed significant increases in group 2 compared to groups 1 and 5. Optimum histoarchitectural protection of the seminiferous tubules was observed in group 2, which did not differ from normal ones. For the hematological parameters, optimum protection was also observed in group 2 compared to other groups. From the results, ethanol seed extract of
C. lanatus
demonstrated protective potentials against aluminum's harmful effects on the male reproductive system and hematology in an experimental male rat model.
کلیدواژههای انگلیسی مقاله
Aluminum chloride,Citrullus lanatus,Rat,Reproduction
نویسندگان مقاله
Rita Ifeoma Odo |
Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria
Chukwuka Nwocha Uchendu |
Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria
Somtoo Ethelbert Okeke |
Department of Veterinary Physiology and Pharmacology, University of Nigeria, Nsukka, Nigeria
نشانی اینترنتی
https://vrf.iranjournals.ir/article_240933_6d468cf0badde267d7f0e21d421174ca.pdf
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