این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Veterinary Research Forum، جلد ۱۱، شماره ۴، صفحات ۳۰۵-۳۰۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The effectiveness of Teucrium chamaedrys L. extracts on endometriotic ‎implant regression in rat endometriosis model
چکیده انگلیسی مقاله The aim of the present study was to investigate the therapeutic effects of Teucrium chamaedrys L. (Lamiaceae) in the experimentally induced endometriosis in rats. Endometrial tissue was implanted into the abdominal wall of thirty Sprague Dawley rats; the rats with endometriosis were randomized into five groups and treatment procedure was performed for three weeks. The treatment groups were orally treated with three different extracts of Teucrium chamaedrys. Buserelin acetate (20.00 mg) was given as a reference drug. Vehicle was administered alone to the control group. All rats were sacrified at the end of the experiment. The endometriotic implants were measured, intra-abdominal adhesions were scored and the tissue samples were histopathologically investigated. After the treatment procedure, the volumes of endometrial implant and adhesions were detected to be significantly decreased in the T. chamaedrys extracts treated groups compared to the control group. Therapeutic effect of the T. chamaedrys extracts could be attributed to the both nonpolar and polar secondary metabolites. The study conceived that the different polarity extracts of T. chamaedrys could be beneficial in the treatment of endometriosis.
کلیدواژه‌های انگلیسی مقاله ‎ Endometriosis,‎ Lamiaceae,‎ Rat,‎ Teucrium chamaedrys
نویسندگان مقاله Sule Ozel |
Clinic of Gynecology, Zekai Tahir Burak Woman’s Health Training and Research Hospital, University of Health Sciences, Ankara, Turkey

Ipek Suntar |
Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara, Turkey

Nilufer Ercan Gokay |
Clinic of Gynecology, Zekai Tahir Burak Woman’s Health Training and Research Hospital, University of Health Sciences, Ankara, Turkey

Tugba Taskin Turkmenoglu |
Department of Pathology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey

Murside Ayse Demirel |
Laboratory Animals Care and Research Unit, Department of Pharmacology, Faculty of Pharmacy, Gazi University, Ankara, Turkey

نشانی اینترنتی https://vrf.iranjournals.ir/article_45645_c0cfc04ac31da2e5c4958ee31de2d57f.pdf
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات