این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Psychiatry، جلد ۱۹، شماره ۱، صفحات ۱۱-۲۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Comparison of Brain Activation According to fMRI Data in Patient with Depression (After Acute Coronary Syndrome and Somatically Healthy) and Healthy Volunteers
چکیده انگلیسی مقاله Objective: The present study is devoted to the study of brain activation using fMRI in patients with depression (after acute coronary syndrome and somatically healthy) and in healthy volunteers. Method: The study enrolled a total of 51 patients: 11 with depression after acute coronary syndrome, 16 with primary depressive episode and recurrent depression without prior coronary event, and 24 with ACS without depression. The groups were matched by sex and age. The emotional information processing was evaluated with the Pennsylvania Test of Emotion Recognition. All patients underwent fMRI at the time of this test. The data processing was performed with SPM12 and xjView applications. Results: During the processing of emotional information in the depressed patients after ACS, specific activation zones in the frontal cortex (P < 0.001), right fusiform gyrus (P < 0.001), and right insular lobe were identified (P = 0.017). In the patients with primary depressive episode and recurrent depression without ACS, certain zones of activation were identified in frontal cortex (P < 0.001; 0.001), left fusiform gyrus (P < 0.001), occipital cortex (P < 0.001). In the patients who had ACS, without depression, some zones of activation were specified in the right middle occipital gyrus (P < 0.001), the right superior frontal gyrus (P = 0.088), and the putamen projection on the right (P < 0.001) and on the left (P = 0.009), as well as the left insular lobe (P = 0.015). Conclusion: The pathogenesis of depression is significantly associated with the peculiarities of processing emotionally significant information, regardless of the conditions under which it develops.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Alena Beliaevskaia
Miasnikov Clinical Cardiology Institute, Moscow, Russia


| Petelin Dmitry Sergeevich
Department of Psychiatry and Psychososmatics, Sechenov University, Moscow, Russia


| Akhapkin Roman Vitalievich
Research Institute of Psychiatry, Branch of the Serbsky State Scientific Center for Social and Forensic Psychiatry, Moscow, Russia


| Volel Beatrice Albertovna
FSBSI Mental Health Research Center, Moscow, Russia


| Ternovoy Sergey Konstantinovich
Department of Radiation Diagnosis and Therapy, Sechenov University, Moscow, Russia
نشانی اینترنتی https://ijps.tums.ac.ir/index.php/ijps/article/view/3624
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات