این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Acta Medica Iranica، جلد ۵۳، شماره ۸، صفحات ۴۷۱-۴۷۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Comparative Evaluation of EGF in Oral Lichen Planus and Oral Squamous Cell Carcinoma
چکیده انگلیسی مقاله Oral lichen planus (OLP) is classified as a potential malignant disorder, and epidermal growth factor (EGF) may play a key role in cancer development. The aim of this study was to compare serum and saliva EGF among patients with OLP and oral squamous cell carcinoma (OSCC). A cross-sectional study was performed on 27 patients with OLP (10 reticular and 17 atrophic-erosive forms), 27 patients with OSCC and 27 healthy control group. The study was conducted at the Cancer Department, Clinic of Oral Medicine, Tehran University of Medical Sciences. The serum and saliva EGF were assayed by ELISA method. Statistical analysis of ANOVA was used. The mean serum EGF in OLP and OSCC patients was significantly lower compared to healthy control group (P < 0.05), but no significant difference was observed between OLP and OSCC patients. There was no significant difference in mean salivary EGF among groups. As serum EGF levels appear to be statistically similar in OLP and OSCC, it seems that EGF might play a role in the pathogenesis of OLP and its cancerization.
کلیدواژه‌های انگلیسی مقاله EGF,Oral lichen planus,Squamous cell carcinoma,Saliva
نویسندگان مقاله فرزانه آقا حسینی | farzaneh agha hosseini
department of oral and maxillofacial medicine, dental research center, tehran university of medical sciences, tehran, iran and department of oral maxillofacial medicine, school of dentistry, tehran university of medical sciences, tehran, iran and department of oral and maxillofacial medicine, the academy of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مینا محبیان | mina mohebbian
department of oral and maxillofacial medicine, dental research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

محمد رضا sarookani | mohammad reza sarookani
department of oral maxillofacial medicine, school of dentistry, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

ایرج حریرچی | iraj harirchi
department of cancer institute, imam khomeini hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

ایرج میرزایی دیزگاه | iraj mirzaii dizgah
department of physiology, school of medicine, aja university of medical sciences, tehran, iran.
نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/4269
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article(s)
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات