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Journal of Midwifery and Reproductive Health، جلد ۱۲، شماره ۱، صفحات ۱-۵
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عنوان انگلیسی Comparison of Helicobacter Pylori Infection in Normal Pregnancy and Preeclampsia
چکیده انگلیسی مقاله Preeclampsia is a hypertensive disorder that affects 2–7% of pregnancies, remaining a major contributor to maternal and fetal mortality and morbidity with uncertain pathogenesis.  Some evidence suggests the role of infectious agents in development of preeclampsia. This study assessed the potential relationship between H. Pylori infection and development of preeclampsia. This case-control study was conducted in one educational hospital in Mashhad, Iran, in 2021. Study participants were selected through convenience sampling. A total number of 34 normotensive and 34 women with preeclampsia in their third trimester enrolled in the study. We assessed serum levels of hemoglobin, hematocrit, platelets, creatinine, and serum levels of H. pylori (IgG and IgA) in all participants, comparing the infection rates between the study groups. There were no significant difference in age, BMI, number of previous pregnancies, hemoglobin, hematocrit, platelet count and creatinine levels among different study groups (P>0.05). The H. Pylori test was positive in 30 (88.2%) pregnant women in preeclampsia group and 23 (67.6%) in the control group (P=0.041). H. Pylori infection was significantly more prevalent in women with preeclampsia compered to healthy pregnant women in third trimester. This suggests a potential association between H. Pylori infection and the development of preeclampsia.
کلیدواژه‌های انگلیسی مقاله Helicobacter pylori, Preeclampsia, pregnancy
نویسندگان مقاله | Masoumeh Mirteimouri
Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Sedigheh Shariatmaghani
Lecturer, Department of Health Education and Health Promotion, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran


| Freshteh Khabir
Medical Doctor, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Maliheh Afiat
Associate Professor, Department of Obstetrics and Gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran


| Shabnam Niroumand
Assistant Professor, Department of Community Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
نشانی اینترنتی https://jmrh.mums.ac.ir/article_23332.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Short Communication
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