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Acta Medica Iranica، جلد ۵۳، شماره ۶، صفحات ۳۴۶-۳۵۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The Effect of Low Omega-3/Omega-6 Ratio on Auditory Nerve Conduction in Rat Pups.
چکیده انگلیسی مقاله The biological effects of omega-3 and omega-6 fatty acids are determined by their mutual interactions. This interaction extremely affects various functions. Lower consumption of omega-3 during gestation leads to various disorders, even in hearing. We aimed to assess the effect of low omega-3/omega-6 ratios on auditory nerve conduction. In this experimental study, the auditory brainstem response test was performed on 24-day-old rat (n=14). The rats were divided into case (low omega-3/omega-6 ratio during gestation and lactation) and control groups. Variables such as P1, P3, and P4 absolute latency period, interpeaks (P3-P4, P1-P3, and P1-P4), and P4/P1 amplitude ratio were measured. We found an increased P4 omega-3/omega-6 ratio in the group with a low omega-3/omega-6 ratio (P 0.05). Also, no significant difference was observed between the groups with respect to the P1-P3 interpeak latency (IPL) periods (P>0.05); while the P1-P4 and P3-P4 IPLs were significantly increased in the group with a low omega-3/omega-6 ratio (P< 0.05). The P4/P1 amplitude ratio significantly decreased in the group with a low omega-3/omega-6 ratio (P< 0.05). Results confirmed the negative effects of low omega-3/omega-6 ratio on the auditory system and hearing.
کلیدواژه‌های انگلیسی مقاله Omega-3 omega-6 ratio,Auditory nerve conduction,Rat pups
نویسندگان مقاله سعید فراهانی | saeid farahani
department of audiology , school of rehabilitation, tehran university of medical sciences,tehran,iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مسعود متصدی زرندی | masoud motasaddi zarandy
department of otolaryngology, school of medicine, tehran university of medical sciences, tehran, iran. and ent research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

غلامرضا حسن زاده | gholamreza hassanzadeh
department of anatomy, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

شیدفر | farzad shidfar
school of health, iran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences)

شهره جلایی | shohreh jalaie
department of biostatistics, school of rehabilitation, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

ویدا رحیمی | vida rahimi
department of audiology, school of rehabilitation, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/4879
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