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International Journal of Nonlinear Analysis and Applications، جلد ۱۴، شماره ۱۱، صفحات ۲۳۳-۲۳۹
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عنوان انگلیسی The essential of applying nonlinear-analysis to validate experiments, assessing superior brain functions: Case-study of a Bayesian-Model of inhibitory control in ADHD
چکیده انگلیسی مقاله In the last decades, nonlinear methods have been applied, in a large number of studies from the computational neuroscience field, to describe neuronal implementations of superior brain functions. Superior brain functions, called cognitive functions, control our behavior. Therefore, they should be assessed by evaluating individual performances in the experiments, using standard tasks, which represent the condition that cognitive functions are required. The mathematical models of cognitive functions, at the neuronal implementation level, are based on the real condition of standard cognitive tasks. However, it is not validated whether applied task conditions are appropriate to represent the neuronal implementation of a cognitive function. Hence, as a case study, we used a developed Bayesian Model to assess whether the GoNoGo task is valid to be applied for neural measurement and modeling neural implementation of Inhibitory Control (IC). As GoNoGo is the most common task used for neural measurement of impaired cognitive function (IC) in ADHD, we fit the model to behavioral data of two groups of children/adolescents with and without ADHD. The results demonstrated that the model could simulate the behavioral data, and also the model parameters could differentiate the groups significantly. However, the neural implementation of IC may not be represented through the rewarded condition of the GoNoGo task. We concluded that before modeling the neural implementation of cognitive functions, it is essential to apply nonlinear methods to validate current behavioral experiments computationally; or to design new model-based experiments for use in neural measurements.
کلیدواژه‌های انگلیسی مقاله Nonlinear-Analysis, Neurocognitive Experiment, Bayesian Model, Cognitive Functions, GoNOGO, ADHD
نویسندگان مقاله Fateme Samea |
Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran

Vahid Nejati |
Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran

Madjid Eshaghi Gordji |
Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran

Reza Khosrowabadi |
Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran

نشانی اینترنتی https://ijnaa.semnan.ac.ir/article_3946_f8056af0363cf249f977dd78543608d7.pdf
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