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Acta Medica Iranica، جلد ۵۲، شماره ۹، صفحات ۶۵۱-۶۵۵

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عنوان انگلیسی Stem cell therapy for treatment of epilepsy.
چکیده انگلیسی مقاله Epilepsy as one of the most common neurological disorders affects more than 50 million people worldwide with a higher prevalence rate in low-income countries. Excessive electrical discharges in neurons following neural cell damage or loss cause recurrent seizures. One of the most common and difficult to treat types of epilepsy is temporal lobe epilepsy (TLE) which results from hippocampal sclerosis. Nowadays, similar to other diseases, epilepsy also is a candidate for treatment with different types of stem cells. Various stem cell types were used for treatment of epilepsy in basic and experimental researches. Two major roles of stem cell therapy in epilepsy are prophylaxis against chronic epilepsy and amelioration cognitive function after the occurrence of TLE. Several animal studies have supported the use of these cells for treating drug-resistant TLE. Although stem cell therapy seems like a promising approach for treatment of epilepsy in the future however, there are some serious safety and ethical concerns that are needed to be eliminated before clinical application.
کلیدواژه‌های انگلیسی مقاله Cell therapy,Epilepsy,Stem cell,Treatment

نویسندگان مقاله پریسا گودرزی | parisa goodarzi
brain and spinal cord injury research center, cellule fanavaran knowledge-based organization, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حمید رضا آقایان | hamid reza aghayan
brain and spinal cord injury research center, cellule fanavaran knowledge-based organization, tehran university of medical sciences, tehran, iran. and endocrinology and metabolism research center, endocrinology and metabolism research institute, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

دکتر مسعود سلیمانی | masoud soleimani
brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran. and department of hematology, faculty of medicine, tarbiat modares university, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

عباس نوروزی جاویدان | abbas norouzi javidan
brain and spinal cord injury research center, cellule fanavaran knowledge-based organization, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

فرشته محمدی جهانی | fereshteh mohamadi jahani
brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

شراره جهانگیری | sharareh jahangiri
brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سید حسن امامی رضوی | seyed hasan emami razavi
brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

باقر لاریجانی | bagher larijani
endocrinology and metabolism research center, endocrinology and metabolism research institute, tehran university of medical sciences, tehran, iran. and medical ethics and history of medicine research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

بابک ارجمند | babak arjmand
endocrinology and metabolism research center, endocrinology and metabolism research institute, tehran university of medical sciences, tehran, iran. and brain and spinal cord injury research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)


نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/4670
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