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Iranian Journal of Medical Sciences، جلد ۴۹، شماره ۱، صفحات ۴۰-۴۵

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عنوان انگلیسی Pulmonary Function Tests in Thunderstorm-associated Respiratory Symptoms: A Cross-sectional Study
چکیده انگلیسی مقاله Background: Epidemic thunderstorm asthma is an observed increase in cases of acute bronchospasm following thunderstorms. This study aimed to compare the frequency of obstructive airway disease or bronchial hyperresponsiveness in subjects with thunderstorm-associated respiratory symptoms with subjects with similar symptoms presented at other times.
Methods: A cross-sectional study from June to November of 2013 was conducted on subjects with thunderstorm-associated respiratory symptoms living in Ahvaz City, Iran. Thunderstorm-associated subjects were presented with asthmatic symptoms in thunderstorms, and other patients presented with similar symptoms at other times. Baseline spirometry was performed on patients to examine the presence of obstructive airway disease. In all patients with normal spirometry, a provocation test was applied. A comparison of qualitative and quantitative variables was made using the Chi-square and independent t test, respectively. All analyses were carried out using SPSS Statistics Version 22. A P value less than 0.05 was considered statistically significant.  
Results: Out of 584 subjects, 300 and 284 participants were in thunderstorm-associated and non-thunderstorm-associated groups, respectively. After the final analysis, 87 (30.6%) and 89 (33.3%) of the thunderstorm-associated subjects and non-thunderstorm-associated group, respectively, had pieces of evidence of airflow limitation (P=0.27). Among the patients with normal spirometry, 161 (81.72%) of the thunderstorm-associated patients and 100 (56.17%) patients of the non-thunderstorm-associated symptoms group had a positive methacholine challenge test result (P<0.001). 
Conclusion: Most of the patients with thunderstorm-associated respiratory symptoms had no obvious evidence of airflow limitation in spirometry.
کلیدواژه‌های انگلیسی مقاله Asthma, Spirometry, Thunderstorm, Methacholine chloride, Respiratory function tests

نویسندگان مقاله Maryam Haddadzadeh Shoushtari |
Air Pollution and Respiratory Diseases Research Center, Enviromental Technologies Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Sakineh Afrakhteh |
Department of Internal Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Seyed Hamid Borsi |
Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Hanieh Raji |
Air Pollution and Respiratory Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Esmaeil Idani |
Chronic Respiratory Diseases Research Center, Shahid Beheshti University of Medical Sciences,Tehran, Iran


نشانی اینترنتی https://ijms.sums.ac.ir/article_49521_a4101aca8a564fec774f2823d09f67d7.pdf
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