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Middle East Journal of Digestive Diseases، جلد ۱۵، شماره ۴، صفحات ۲۴۲-۲۴۸
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عنوان انگلیسی Predictors of Pathological Gastroesophageal Reflux among Emirati Patients with Reflux Symptoms Who Undergo Wireless pH Monitoring
چکیده انگلیسی مقاله Background :  Diagnosis of gastroesophageal reflux disease (GERD) relies on recognizing symptoms of reflux and mucosal changes during esophagogastroduodenoscopy (EGD). The desired response to acid suppression therapy is reliable resolution of GERD symptoms; however, these are not always reliable, hence the need for pH testing in unclear cases. Our objective was to identify potential predictors of a high DeMeester score among patients with potential GERD symptoms to identify patients most likely to have pathological GERD. Methods:  We conducted a retrospective case-control study on patients who underwent wireless pH monitoring from January 2020 to April 2022. Cases were patients with a high DeMeester score (more than 14.7), indicating pathological reflux, and controls were those without. We collected clinical and demographic data, including age, sex, body mass index (BMI), smoking status, non-steroidal anti-inflammatory drugs (NSAID) use, and presence of atypical symptoms. Results: 86 patients were enrolled in the study. 46 patients with high DeMeester scores were considered cases, and 40 patients with DeMeester scores less than 14.7 were considered controls. Esophagitis (grade A) was found in 41.1% of the cases and in 22.5% of the control group. In our study, age of more than 50 years compared with age of 20-29 years and being overweight appeared to be predictors of true pathological reflux among patients with reflux symptoms who underwent wireless pH monitoring. Conclusion: Age above 50 years compared with age between 20-29 years and being overweight appeared to be predictors of true pathological reflux among patients with reflux symptoms who underwent wireless oesophageal pH monitoring. The presence of oesophagitis was approximately four times more likely to be associated with true pathological reflux.
کلیدواژه‌های انگلیسی مقاله Gastroesophageal reflux disease, Epidemiology, Age, DeMeester score, Wireless PH capsule
نویسندگان مقاله | Mostafa Ahmed Shehata


| Talha Aziz Malik


| Mona Jasem Alzaabi


| Ameirah Bader Alali


| Khalifa Saleh Alteniaji


| Yashbir Singh


| Michael Bradley Wallace


نشانی اینترنتی http://mejdd.org/index.php/mejdd/article/view/2860
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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