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Journal of Cardio-Thoracic Medicine، جلد ۱۱، شماره ۳، صفحات ۱۲۰۷-۱۲۱۵

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عنوان انگلیسی Determinants of Serum Vitamin D level; A Data Mining Approach
چکیده انگلیسی مقاله Introduction:  Serum vitamin D levels are related to a wide spectrum of factors including low sunlight exposure, high oxidative stress, low physical activity and sleep disorders. In this paper we are going to investigate the most crucial parameters associated with serum vitamin D levels in survey of ultraviolet intake by nutritional approach (SUVINA) study with a data mining approach.Material and Methods: Data including demographic, anthropometric, clinical and laboratory information were extracted from the SUVINA dataset comprising 289 subjects who were enrolled into our study. The XGBoost algorithm was used to define the most important features related to vitamin D level in our population.Results: Applying XGBoost modeling for vitamin D level showed that the presented scheme can determine the most important determinants of serum vitamin D level with an accuracy of 91%. Pro-oxidant anti-oxidant balance (PAB), body fat percentage, physical activity level (PAL), age, restless leg syndrome (RLS), and dietary inflammatory index (DII) density were the most important variables correlated with vitamin D deficiency.Conclusion: Using XGBoost and with an accuracy of more than 90%, we showed that the six most important risk factors for vitamin D deficiency are PAB, PAL, age, body fat percentage, RLS and DII density, respectively.
کلیدواژه‌های انگلیسی مقاله Vitamin D, Oxidative stress, Machine Learning, Data Mining Algorithm

نویسندگان مقاله | Zahra Amiri
Department of Pure Mathematics, Center of Excellence in Analysis on Algebraic Structures (CEAAS), Ferdowsi University of Mashhad, P.O. Box 1159, Mashhad 91775, Iran.|International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


| Fahimeh Moafian
Department of Pure Mathematics, Center of Excellence in Analysis on Algebraic Structures (CEAAS), Ferdowsi University of Mashhad, P.O. Box 1159, Mashhad 91775, Iran.|International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


| Payam Sharifan
International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.|Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.|Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Elahe Hasanzadeh
Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Zahra Khorasanchi
Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Moniba Bijari
International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


| Maryam Mohammadi Bajgiran
International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


| Sara saffar soflaei
International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


| Susan Darroudi
International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.


| Hamideh Ghazizadeh
International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.|Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| fatemeh rouhi
Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Fatemeh Mohseni nik
Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Maryam Tayefi
Norwegian Center for E-Health Research, University Hospital of North Norway, Tromsø, Norway.


| Samira roohi
Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.


| Ayad Noor
Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.


| Abdullah Al yakobi
Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.


| Mohammed Hadi Lafta Alboresha
Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.


| Gordon A. Ferns
Division of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex, UK.


| Habibollah Esmaily
Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.


| Majid Ghayour-Mobarhan
International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.|Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.



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