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Iranian Journal of Pathology، جلد ۱۹، شماره ۱، صفحات ۳۱-۴۹
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عنوان انگلیسی Comprehensive Analysis of the Prognostic Marker and Immune Infiltrates of LDLR-Related Proteins Family Members in Breast Cancer
چکیده انگلیسی مقاله Breast cancer is one of the common malignant tumors worldwide accounting for 15% of all cancer-related deaths. Since a timely diagnosis of BC is essential for optimal treatment and also increasing the survival rate of patients. Today, various financial support is applied to find the best biomarkers. Considering the financial issue, in-silico analysis is the best approach. LRP family proteins are important components of cell-surface receptors that involved in numerous biological activities. One of the most pivotal role LRPs is Wnt signaling pathway. Expression of LRP is related with BC malignancy. In this study, we first investigated expression of LRPs in BC tissues in comparison with normal tissues. Relation of LRP expression with RFS and OS. Then, we investigated the association of LRPs expression and immune infiltrating abundance.
کلیدواژه‌های انگلیسی مقاله Breast cancer, Immune Infiltration, LDLR-related protein, prognostic marker
نویسندگان مقاله Negin Parsamanesh |
Vali-e Asr Hospital, Zanjan, Iran

Shabnam Shahidi |
Vali-e Asr Hospital, Zanjan, Iran

Parvin Ansari Shayesteh |
Department of Molecular Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

Mahsa Alami |
Vali-e Asr Hospital, Zanjan, Iran

نشانی اینترنتی https://ijp.iranpath.org/article_709737_a1a85c3db181ef8a92cb60a42fa9ac76.pdf
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