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Acta Medica Iranica، جلد ۵۰، شماره ۸، صفحات ۵۳۰-۵۳۴

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عنوان انگلیسی A Novel Protocol for Gastric Lavage in Patients with Aluminum Phosphide Poisoning: A Double-Blind Study
چکیده انگلیسی مقاله Aluminum phosphide poisoning (ALPP) still has no efficient and approved antidote. Supportive care and hemodynamic monitoring are the only choices of treatment. We proposed a new lavage formulation in addition to evaluation of its efficacy and defining the impact of clinical characteristics of patients on their prognosis. During eight months period of time, 120 patients were enrolled to the study and randomly received two different gastric lavage protocols. Our new lavage protocol had positive impact on patients' survival and the P-value in comparison with the classic gastric lavage method was close to significant level (P=0.054). On hospital arrival indication for intubation-ventilation as well as sense of thirst, sore throat and absence of nausea indicate worse outcome. Using our novel approach, indication for intubation-ventilation as well as sense of thirst, sore throat and absence of nausea can be considered as applicable prognostic factors in survival of ALPP patients. Further studies are required to set this approach as preferred treatment.
کلیدواژه‌های انگلیسی مقاله Aluminum Phosphide,Poisoning,Gastric lavage,Novel treatment

نویسندگان مقاله بابک مصطفی زاده | babak mostafazadeh
department of forensic medicine and toxicology, loghman hakim hospital poison center, shahid beheshti university of medical sciences, tehran, iran. and toxicological research center, shahid beheshti university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

اسماعیل فرزانه | esmaeil farzaneh
department of forensic medicine and toxicology, ardabil university of medical sciences, ardabil, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)


نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/3943
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زبان مقاله منتشر شده en
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