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Archives of Breast Cancer، جلد ۱۱، شماره ۱، صفحات ۱-۱۲
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عنوان انگلیسی Immunopathological Mechanisms Observed in the Intratumoral Microenvironment and Their Relationship with Worse Prognosis in Triple-Negative Breast Cancer: Immunopathological mechanisms in TNBC
چکیده انگلیسی مقاله Background: In the 21st century, the main cause of death in both sexes worldwide is cardiovascular disease, followed by neoplasms. In women, the main cause of morbidity and mortality is breast cancer. Therefore, understanding the immunological mechanisms associated breast cancer and its correlation with poor prognosis is very important. Methods: In this study, a search was done on PubMed and Google Scholar, using the following medical subject headings (MeSH) in the search engine: “triple negative breast cancer”, “breast cancer microenvironment”, “immune cells”, “prognosis”, “regulatory t reg”, “T cells” and “tumor-associated neutrophils”. Thus, a total of 81 articles were found and reviewed, published between 2002 and 2023. Results and conclusions: It is essential to understand the immunological mechanisms associated with the tumor microenvironment, to create new targeted treatment schemes for each variant of breast cancer, for example triple negative in order to reduce the mortality rate and increase disease-free survival. 
کلیدواژه‌های انگلیسی مقاله Triple negative breast cancer, immunology, tumor microenvironment, tumorigenesis, immunotherapy
نویسندگان مقاله | Josué Mondragón Morales
Escuela Superior de Medicina, Instituto Politécnico Nacional, Salvador Díaz Mirón esq. Plan de San Luis S/N, Miguel Hidalgo, Casco de Santo Tomás, México City, México


| Rogelio Rogel-Alvarado
Facultad de Enfermería y Obstetricia, Universidad Nacional Autónoma de México, Camino Viejo a Xochimilco y Viaducto Tlalpan S/N. San Lorenzo Huipulco, Tlalpan, México City, México


| Iris Alejandra Noverón-Figueroa
Escuela Superior de Medicina, Instituto Politécnico Nacional, Salvador Díaz Mirón esq. Plan de San Luis S/N, Miguel Hidalgo, Casco de Santo Tomás, México City, México


| Max Morales-Gutierrez
Universidad Westhill, Domingo García Ramos Nº 56, Cuajimalpa Col. Prados de la Montaña, México City, México
نشانی اینترنتی https://archbreastcancer.com/index.php/abc/article/view/834
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi) 10.32768/abc.20241111-12
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Review Article
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