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Archives of Breast Cancer، جلد ۱۱، شماره ۱، صفحات ۷۵-۸۱
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چکیده فارسی مقاله
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عنوان انگلیسی Axillary Lymph Node Coverage in Breast Cancer Patients Treated with Adjuvant Radiation Using High Tangent Fields Technique: A Single Institution’s Experience: High tangent adjuvant radiotherapy
چکیده انگلیسی مقاله Background: The high tangent field (HTF) technique is used to provide radiation coverage of the inferior axillary nodal levels for breast cancer patients when the lower axilla is at risk for micrometastatic disease. Despite its use in clinical practice, there is concern about whether HTF provide sufficient coverage of level I and II axillary nodal regions. The purpose of this study is to quantify and evaluate the coverage of HTF at our institution. Methods: Patients diagnosed with early invasive breast carcinoma (pT1-2 pN0-1a) who received HTF radiation between January 1st, 2012 and December 31st, 2016 were retrospectively reviewed. Level I and II axillary nodal regions were contoured on each patient’s simulation CT. Dosimetric parameters were re-calculated to evaluate coverage. Statistical analysis was conducted using Mann-Whitney-U method.  Results: Thirty-seven patients with low-risk breast adenocarcinoma were included. For level I and II, the mean V90% was 94.63% ± 7.60% and 73.33% ± 21.83% respectively. Twenty-nine patients received adequate V90% coverage of level I and had a mean level II V90% of 76% ± 18.71% while eight patients who did not receive adequate V90% level I coverage had a mean level II V90% of 63.64% ± 30.22%. The median level II V90% of patients receiving adequate and inadequate level I V90% was 77.74% and 71.11% respectively; the difference was not statistically significant (P = 0.33). Conclusion: HTF provides adequate coverage for level I nodes, but inadequate coverage for level II. Contouring nodal volumes may assist field placement and improve nodal volume coverage.
کلیدواژه‌های انگلیسی مقاله radiation, breast cancer, Adjuvant radiotherapy
نویسندگان مقاله | Lindsay Booth
Faculty of Medicine, University of British Columbia, Kelowna, BC, Canada


| Timothy Kong
Division of Radiation Oncology and Developmental Radiotherapeutics, Department of Surgery Faculty of Medicine, University of British Columbia, Vancouver, Canada; BC Cancer - Vancouver, Canada


| Ajhmair Lali
Faculty of Medicine, University of British Columbia, Kelowna, BC, Canada


| Angela Lin
Division of Radiation Oncology and Developmental Radiotherapeutics, Department of Surgery Faculty of Medicine, University of British Columbia, Vancouver, Canada; BC Cancer - Kelowna, Canada


| François Germain
Division of Radiation Oncology and Developmental Radiotherapeutics, Department of Surgery Faculty of Medicine, University of British Columbia, Vancouver, Canada; BC Cancer - Kelowna, Canada


| Sarah Lucas
Division of Radiation Oncology and Developmental Radiotherapeutics, Department of Surgery Faculty of Medicine, University of British Columbia, Vancouver, Canada; BC Cancer - Kelowna, Canada


| Rasika Rajapakshe
Faculty of Medicine, University of British Columbia, Kelowna, BC, Canada; BC Cancer - Kelowna, Canada; Computer Science, UBC Okanagan, Kelowna, Canada


| Siavash Atrchian
Division of Radiation Oncology and Developmental Radiotherapeutics, Department of Surgery Faculty of Medicine, University of British Columbia, Vancouver, Canada; BC Cancer- Kelowna, Canada
نشانی اینترنتی https://archbreastcancer.com/index.php/abc/article/view/848
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi) 10.32768/abc.202411175-81
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
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