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Acta Medica Iranica، جلد ۴۹، شماره ۱۲، صفحات ۷۸۰-۷۸۳

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عنوان انگلیسی Study to Evaluate Two Dosage Regimens of Vitamin D through an Academic Year in Middle School Girls: a Randomized Trial
چکیده انگلیسی مقاله Vitamin D is an essential hormone for growth and development of bones in children. There is a lot of evidence for deficiency of this vitamin in Middle East females. This study conduct to find a way to combat deficiency in girls during rapid growth phase of puberty in academic year. One hundred and two Middle School girls who had not consumed any vitamins supplement have been participated in this randomized clinical trial. They allocated randomly in two case groups who received 50,000 or 100,000 IU vitamin D3 in October and three months later in January or in control group who received vitamin E. At the end of winter blood samples for 25-hydroxyvitamin D were checked. The mean of 25-hydroxyvitamin D were 5.5±1.5 ng/ml, 15.2±6 ng/ml, 23.0±6.8 ng/ml in control, 50,000 and 100,000 IU vitamin D groups respectively (P0.05). Urine calcium/creatinin ratio was equal in case and control groups (P>0.05). 100,000 IU of vitamin D3 every three months (equal to 800IU/day) can raise 25-hydroxyvitamin D above 12 ng/ml in all cases but for area with high prevalence of sever deficiency, dosage more than 100,000 IU every three months or shorter interval recommended to achieve optimal level.
کلیدواژه‌های انگلیسی مقاله 25-OH vitamin D,Girl,Dietary supplement,Bolus dose

نویسندگان مقاله شکیبا | mehrdad shakiba
department of pediatric, shahid sadoghi university of medical sciences, yazd, iran.


ملیحه قدیر | malihe ghadir
internal medicine, school of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

زهرا نفعی | zahra nafei
department of pediatric, shahid sadoghi university of medical sciences, yazd, iran.


صدیقه اخوان کرباسی | sedighe akhavan karbasi
department of pediatric, shahid sadoghi university of medical sciences, yazd, iran.


محمد حسن لطفی | mohammad hassan lotfi
department of biostatics, faculty of health, shahid sadoghi university of medical sciences, yazd, iran.


احمد شجری | ahmad shajari
department of pediatric, shahid sadoghi university of medical sciences, yazd, iran.



نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/3838
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