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Avicenna Journal of Phytomedicine، جلد ۱۴، شماره ۲، صفحات ۲۴۲-۲۵۱
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چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Metabolic and endocrine changes induced by cinnamon in women with polycystic ovarian syndrome: A pilot study
چکیده انگلیسی مقاله Objective: Most polycystic ovary syndrome (PCOS) patients have metabolic abnormalities in which insulin resistance (IR) plays a pivotal role. Cinnamon is a herbal medicine with insulinotropic properties. This pilot study aimed to evaluate the effects of cinnamon on ovarian volume, androgenic profile, and metabolic and anthropometric parameters in women with PCOS.Materials and Methods: A single-center, double-blind, randomized, placebo-controlled trial was carried out on 39 overweight / obese women with PCOS. For six months, subjects in the cinnamon (500 mg) (n=19) and placebo (n=20) groups were given three capsules daily. Before and after the intervention, the variables were assessed. The data was analyzed using the GraphPad Prism software.Results: After the intervention, the two intervention and control groups had significant differences in abdominal subcutaneous fat and ovarian volume, but they did not differ significantly in terms of body mass index (BMI). Also, after the intervention, no significant difference was observed between the two groups in terms of lipid profile and the concentration of androgenic biomarkers of insulin resistance.Conclusion: Cinnamon supplementation improves ovarian volume and subcutaneous abdominal fat but has no effect on anthropometric parameters, lipid profile, insulin resistance, or androgen hormones.
کلیدواژه‌های انگلیسی مقاله Cinnamon, Polycystic Ovarian Syndrome, Menstruation, insulin resistance, Lipids, Abdominal fat
نویسندگان مقاله | Sepideh Peivandi
Sexual and Reproductive Health Research Center, Department of OB/GYN, IVF Ward, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran


| Sahar Heydari-latibari
Department of OB/GYN, IVF Ward, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran


| Fatemeh Ghasemzadeh
Department of OB/GYN, IVF Ward, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran


| Marzieh Zamaniyan
Diabetic Research Center, Department of OB/GYN, IVF Ward, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran


| Adele Bahar
Department of Endocrinology, Diabetic Research Center, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran


| Hadi Majidi
Department of Radiology, Sari Imam Khomeini Hospital, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran


| Behnam Maleki
IVF Ward, Sari Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Iran
نشانی اینترنتی https://ajp.mums.ac.ir/article_23357.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Research Article
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