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Acta Medica Iranica، جلد ۴۷، شماره ۵، صفحات ۳۶۹-۳۷۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effects of Different Doses of Hyaloronan on Human Sperm Motility, Vitality and Morphology
چکیده انگلیسی مقاله Important aspect of sperm function such as motility and capacitation appear to be mediated at least partially though hyaloronic acid (HA). Present study investigated effects of different doses of HA on sperm motility and vitality in human. Sperm was obtained from 20 male from IVF clinic in Imam Khomeini Hospital. Sperm motility and vitality in human semen was analyzed according to WHO criteria before and 4 hours after treatment with different doses of HA (0.750, 1000 and 1250 µg/ml). The results showed that in 1000 µg/ml the percent of stage 3 and 4 increased compare to control group. Percent of stage 1 and 2 decreased in group with 1000 µg/ml HA, there was an increase in the percentage of stage 3 and 4 and decrease in percentage of stage 1 and 2 compare to control. In the group treated with 1250 µg/ml stage 1 and 2 increased while stage 3 and 4 decreased. Vitality in all groups decreased except of the group treated with 1000 µg/ml HA. The group with 1250 µg/ml showed significantly decrease in vitality compare to fresh group ( P < 0.05). The present study showed that the effects of HA on sperm motility and vitality is dose dependant and 1000 µg/ml HA had the effective role on sperm parameters.
کلیدواژه‌های انگلیسی مقاله Human sperm,hyaloronan,sperm parameters
نویسندگان مقاله آمنه محمدی روشنده | amaneh mohammadi roushandeh
department of anatomy, school of medicine, tabriz university of medical sciences, tabriz, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

فرناز سهراب وند | farnaz sohrabvand
vali-e-asr reproductive health research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سعید امان پور | saeid amanpour
vali-e-asr reproductive health research center, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

پریچهر پاسبخش | parichehr pasbakhsh
department of anatomy, faculty of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

عبدالله سبحانی | abdollah sobhani
department of animal sciences, faculty of agriculture, university. of mohghegh ardabili, ardabil, iran.


حسین نیکزاد | hossein nikzad
department of anatomy, faculty of medicine, kashan university of medical sciences, kashan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کاشان (Kashan university of medical sciences)

علیقلی سبحانی | aligholi sobhani
department of anatomy and vali-e-asr reproductive health research center, faculty of medicine, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی http://acta.tums.ac.ir/index.php/acta/article/view/3609
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