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Iranian Journal of Basic Medical Sciences، جلد ۲۷، شماره ۵، صفحات ۵۳۵-۵۴۲
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عنوان انگلیسی Preclinical models of atherosclerosis: An overview
چکیده انگلیسی مقاله Atherosclerosis is a primary cause of illness and death globally and its mechanism is still unclear. Different animal models have been created to evaluate the progression of atherosclerosis, allowing researchers to carefully control the circumstances of the experiment as well as the nutrition and environmental risk factors. To investigate the negative effects of various interventions, pathophysiological alterations might be generated utilizing genetic or pharmacological methods. These models’ molecular and pathophysiological mechanisms have been clarified through experiments, and they have served as platforms for the creation of new drugs. Different models can be employed to address various research problems, each with its own benefits and drawbacks. In the current review study, various species of atherosclerosis models are discussed, along with the viability of using them in experiments.
کلیدواژه‌های انگلیسی مقاله Atherosclerosis, Cardiovascular Disease, Diets, Inflammation, Low-density lipoprotein
نویسندگان مقاله | Priyanka Arya
Galgotias College of Pharmacy, Greater Noida, U.P., India


| Vikram Sharma
Galgotias College of Pharmacy, Greater Noida, U.P., India


| Surabhi Thapliyal
Department of Pharmacology, All India Institute of Medical Sciences, Rishikesh 249203, India


| Rahul Sagar
AnovIP, New Delhi, India


| Priyanka Singh
Galgotias College of Pharmacy, Greater Noida, U.P., India
نشانی اینترنتی https://ijbms.mums.ac.ir/article_23812.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Review Article
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